On the Horizon – Targeting Bones in the Treatment of Advanced Prostate Cancer
Osteoblasts and osteoclasts are the process that the body uses to breakdown old bone and then to rebuild it with new bone. c-Met is a tyrosine kinase expressed by osteoblasts and osteoclasts, and overexpressed by [...]
Laptop Computer Exposure Associated With Non-Thermal Effect on Sperm Quality & Maybe Prostate Cancer
Are you the kind of guy that uses his laptop computer in your lap? Many of us do this when we are in our car or even seated on our couch while we watch TV. [...]
What is the Current Role of Taxanes in the Treatment of Metastatic Prostate Cancer?
Since it FDA approval in 2004, docetaxel (a taxane based chemotherapy) has been the standard first-line chemotherapy for men with metastatic prostate cancer (mCRPC). Other than the trial of Provenge all the successful phase III [...]
PET/MR Imaging More Efficacious for Mapping Recurrent Prostate Cancer
Approximately one third of all men diagnosed and treated for prostate cancer will experience a recurrence of their prostate cancer! This is a shocking number, but it is a true number. It does not matter [...]
Start A Cure Project of the Day – Extending “Off Periods” of ADT
Start A Cure Research Project of the Day A Simple and Novel Approach to Enhance the Efficacy of Intermittent Androgen Deprivation Therapy for Prostate Cancer Patients There comes a time when most of us will [...]
Using Denosumab (Xgeva) To Combat Skeletal Complications in Prostate Cancer
Xgeva is a monoclonal antibody that inactivates RANKL, a protein that enhances osteoclast activity and survival. By inhibiting RANKL, Xgeva prevents skeletal-related events in men with bone metastasis from prostate cancer. Under no circumstances should [...]