osteoblasts

Understanding the Complexities of Bone Metastases in Prostate Cancer

Our bones operate in a balanced and dynamic system, which in the normal situation keep them strong. Bones are constantly being eliminated and then remade to keep them healthy and read to support our frame. This normal process involves two major kinds of bone cells that work together, in balance, to keep bones healthy and [...]

By Malecare|2017-10-19T10:47:31-04:00February 6th, 2015|Advanced Prostate Cancer, Bone Health, Bone Metastases, Uncategorized, Understanding APC|2 Comments

On the Horizon – Targeting Bones in the Treatment of Advanced Prostate Cancer

Osteoblasts and osteoclasts are the process that the body uses to breakdown old bone and then to rebuild it with new bone. c-Met is a tyrosine kinase expressed by osteoblasts and osteoclasts, and overexpressed by prostate cancer cells. This over expression leads to the eventual development of bone metastases. The experimental treatment known as Cabozantinib [...]

By Malecare|2017-10-19T10:49:44-04:00June 21st, 2013|Advanced Prostate Cancer, Bone Metastases, cabozantinib, Clinical Trials, Clinical Trials, Drugs & Treatments, On The Horizon, Uncategorized, Understanding APC|0 Comments