18F-Fluciclovine PET/CT Superior to 11C-Choline PET/CT for the Detection of a Prostate Cancer Relapse

We have all been ever increasingly aware of the weakness of our scanning technologies when it comes to both diagnosing prostate cancer and its recurrence. Given that about 1/3 of all primary treatments for prostate cancer will fail and the cancer will return it is vital that we improve our ability to detect prostate cancer [...]

Is There A Role For Surgery In Men With Nodal Oligometastatic Prostate Cancer After A Biochemical Failure?

Recently there have been a number of conversations in the prostate media around the topic of treating oligometastatic prostate cancer with a curative goal. Oligometastatic prostate cancer describes the disease state where primary treatment has failed as evidenced by an increasing PSA along with scanning evidence of a limited number of lymph nodes involved in [...]

Using choline-C11 PET/CT Scans To Predict Survival In Men With Recurrent Prostate Cancer

Choline-C11 PET/CT scans can identify the actual sites of recurrence of prostate cancer in men who have a rising PSA after receiving primary therapy. The question worth asking is if this type of scan might be able to be used for prognostic purposes. Knowing this might influence our treatment decisions as well as our basic [...]

Choline C-11 A Second Shot To Halt The Cancer After Primary Treatment Failure

The dirty little secret that is kept from most of us when we receive primary treatment for prostate cancer is that there is a recurrence rate approaching 33%. This amazingly high rate is consistent no matter what primary treatment is elected. Radiation, surgery, HIFU the rates are the same, about 1/3 of us will experience [...]

Commonly Used FDA Approved Treatments for Metastatic Castrate Resistant Prostate Cancer (mCRPC)

The first line of treatment for advanced prostate cancer is Androgen (male hormone) Deprivation Therapy or ADT. Once the PSA progresses (climbs) while still on ADT and with testosterone levels

Video Description of the the C-11 Choline Scan by Dr. E. Kwon From the PCRI Conference

At last year's PCRI Patient Conference Dr. Eugene Kwon from the Mayo Clinic gave a talk about the use of the C-11 Choline PET Scan for me with castrate resistant prostate cancer who have had a recurrence. Specifically, he described his patients as "Failure Patients" or advanced prostate cancer patients who have failed primary treatments [...]

PET/MR Imaging More Efficacious for Mapping Recurrent Prostate Cancer

Approximately one third of all men diagnosed and treated for prostate cancer will experience a recurrence of their prostate cancer! This is a shocking number, but it is a true number. It does not matter what the treatment a man has, the statistic holds up across all treatments. The first sign of a problem, a [...]

More Information About C11 Choline Scans & Some of the Other Alternative Scans Used to ID Focal Advanced Prostate Cancer Recurrences

Off-line I have received a number of additional questions about the use of imaging with c11 choline (see my post at http://advancedprostatecancer.net/?p=3433). The questions ranged from what is c11 choline to how it compares to some of the other more sensitive PET scans contrasts that are being used to identify specific locations of recurrent advanced [...]

A Great Stride In PET Imaging, But Not A Panacea – C11 Choline For Diagnosing Recurrent Prostate Cancer

The FDA has approved c11 choline Injection, a Positron Emission Tomography (PET) imaging agent, for use in men to detect prostate cancer recurrences and to locate specific body sites for follow-up tissue sampling, testing and treatment. The indicated use for c11 choline injection is men with elevated prostate specific antigen (PSA) levels after earlier primary [...]

So Much Has Happened While I was Away – News About Advanced Prostate Cancer

The summer is coming to a close and I am back, ready to again take on the world. I had the fantastic opportunity of spending almost two weeks in Alaska, a land that is so different from the lower 48. I have to say that I have a new found respect for those individuals who [...]