HSD3B1 gene makes Androgen Deprivation Therapy (ADT) less effective
An inherited genetic change, HSD3B1 gene causes Androgen Deprivation Therapy (ADT) to be less effective for treating metastatic prostate cancer. Physician-researcher Nima Sharifi, M.D. published this finding in the October, 2016 The Lancet Oncology. While Androgen Deprivation Therapy is effective for many [...]
A New Steroid for Treating Advanced Prostate Cancer
E4 is a steroid that may become a treatment for advanced prostate cancer, both alone and fin combination with hormone therapy. Ellen Dutman, MSc, a clinical researcher, studied E4 as a treatment to lower testosterone. [...]
Androgen Deprivation and Dementia “Might” be Linked
Androgen deprivation therapy (ADT, or, “hormone therapy”) may be linked to increased risk of having dementia. Researchers, Nead, Sinha and Nguyen reviewed nine studies by other researchers. Seven of those studies reported an adjusted effect [...]
Yervoy ( Ipilimumab ) Useless When Used By Itself
Yervoy (ipilimumab) alone doesn’t help treat advanced prostate cancer patients. Yervoy activates the immune system by going after the CTLA-4 protein receptor that slows immune-system activity. But prostate cancer responds to Yervoy by increasing two other immune [...]
Selective Androgen Receptor Degraders May Become New Treatment for Castration Resistant Prostate Cancer
New molecules called selective androgen receptor degraders (SARDs) might be helpful in fighting advanced prostate cancer, according to an industry-sponsored study presented April 1, at the 99th annual meeting of the Endocrine Society. "If successful [...]
Estrogen As New Prostate Cancer Treatment
Fetal estrogen estetrol, also called E4, is being tested in the Netherlands as a treatment for advanced prostate cancer. "E4 for the treatment of prostate cancer would offer a new and affordable option compared to [...]