Taxane-Based Chemotherapy Drugs May Be Underestimated, Especially Against Advanced Prostate Cancer

According to researchers at Weill Cornell Medical College in the Sept. 15 issue of the journal Cancer Research, taxne-based chemotherapy drugs are not well understood as they may be more powerful than many have believed. Generally, it is believed that taxane chemotherapy (paclitaxel, docetaxel and cabazitaxel) just stop a cancer cell from dividing -- but [...]

No Reduction in Mortality for Men with Localized Prostate Cancer who had a Prostatectomy

In an updated study published in the New England Journal of Medicine men who had a radical prostatectomy did not enjoy the experience of a reduced all-cause mortality or prostate cancer mortality compared with those men who had only observation through several years of follow-up. The subject men had localized prostate cancer often detected by [...]

Impact of Postoperative PSA Scores on Recurrence and the use of Salvage Therapy on the Risk of Death

In a study conducted by Choueiri et al. published in Cancer it was suggested that men who have prostate cancer that was treated by a radical prostatectomy (RP) who then had a long time to a biochemical recurrence (BCR) or a long PSA doubling time after a BCR have no higher overall risk of death [...]

A Weed Killer Drug From Mediterranean Kills Prostate Cancer Tumor Cells

Johns Hopkins Kimmel Cancer Center along with Danish researchers have announced the development of a novel, investigational anticancer drug (G202) that has been described as a molecular grenade that targets cancer cells. The drug is able to travel undetected by normal cells through the bloodstream until it is activated by a specific cancer proteins, then [...]

$40 for your thoughts about Advanced Prostate Cancer

Here's a great opportunity to participate in an advanced prostate cancer marketing survey, earn $40 dollars for yourself and help move our understanding of our disease just a little bit further forward. What is the purpose? Understanding patients' knowledge and perceptions of treatments for prostate cancer, so researchers can understand how prostate cancer affects patients [...]

By |2017-10-19T10:51:02-04:00June 21st, 2012|Advanced Prostate Cancer, Research, Uncategorized|0 Comments

Towards A Biomarker To Predict Survival in Advanced Prostate Cancer

According to the results of a study published in the Journal of Clinical Oncology a bone scan index (BSI) can assess response to treatment and predict survival in metastatic hormone-refractory prostate cancer. Men who have castrate resistant or metastatic hormone-refractory prostate cancer that no longer responds to hormonal therapy and has spread to distant sites [...]

On the Horizon – TOK-001 (Galeterone)

Tokai, a Cambridge, MA based Pharmaceutical company, just presented a promising set of Phase I data pointing to the early efficacy of its "triple whammy" pill for castration-resistant prostate cancer, TOK-001 or galeterone. In their phase 1 trial the PSA levels in about half of the 49 men in the dose-ranging study declined 30% or [...]

A New Genetic Technique Predicts Prostate Cancer Relapse

According to a study published online May 9 in The American Journal of Pathology copy number variations (CNV) in both malignant and benign prostate tissue is predictive of prostate cancer relapse. The research performed at the University of Pittsburgh School of Medicine by Yan P. Yu, M.D. and colleagues evaluated whether CNV of the genomes [...]

Good News – We Have Made It Over Another Funding Hurdle for the Department of Defense Medical Research Program for Fiscal 2013

Yesterday May 16, 2012, the House Appropriations Committee released their draft committee report to accompany the FY13 Defense Appropriations Act. This draft included the CDMRP requested budget for 2013. The good news is that the ask includes $80 million dollars for the Prostate Cancer Research Program. Although this is the same amount prostate cancer received [...]

New Data Indicates That Provenge Works Best In Men With Lower PSA Scores

Today, May 16, 2012, Dendreon, the makers of Provenge, disclosed a new analysis of data of its pivotal 512-patient study of men with castrate resistant prostate cancer who received sipuleucel-T (Provenge). The new analysis separated the men in the study into four quartiles based on their prostate-specific antigen (PSA) scores. The initial design of the [...]

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