The Well Reviewed Guide to Advanced Prostate Cancer (A Survivor Perspective) Has Been Updated and is Now Available for a free Download

Somehow I have been negligent and not let people know that I have written and posted a major update of my “Guide to Advanced Prostate Cancer.” As in the past, it is available as a free download from the Malecare web site. Helping me to update the book was prostate cancer survivor Craig Pynn and [...]

Inflammation Negatively Impacts Overall Survival of Men with Advanced Prostate Cancer

The commonly used serum (blood) marker for inflammation is C-reactive protein (CRP).  It is believed that CRP has a prognostic impact for men with metastatic prostate cancer (MPC) (advanced prostate cancer). The researchers conducted a meta-analysis to quantitate its prognostic impact. They conducted asystematic review to identify publications and presentations exploring the association of baseline [...]

Understanding & Treating Radiation Proctitis Resulting from Prostate Cancer Treatment

One of the more common side effects of primary prostate cancer treatment with any form of x-ray or ionizing radiation is known as radiation proctitis and the related radiation colitis. Radiation proctitis is inflammation and damage to surrounding organs and tissue caused by stray radiation. Radiation proctitis most commonly occurs after treatment for many different [...]

The Positive Effects of Endurance Training for Men with Advanced Prostate Cancer On ADT

All of us on androgen deprivation therapy (ADT) know that without testosterone our bodies change and we will develop insulin resistance, the precursor to diabetes. In a just very small, just published study investigators examined if endurance training would improve insulin sensitivity and body composition in men being treated with ADT for their advanced prostate [...]

Two More Provenge Related Abstracts from the 2013 ASCO GU Symposium

More on Sipuleucel-T (Provenge) from the 2013 The last two abstracts that I want to speak about that were presented at the conference that pertained to Provenge speak to its efficacy. The first looks at changes in circulating tumor cells (CTC) and the second to the onset of the use of opioid painkillers. Abstract #40 [...]

From the 2012 AACR Meeting – Systemic Inflammation and Survival in Men with Prostate Cancer: Evidence from the Glasgow Inflammation Outcome Study.

I met with Dr. Kashif Shafique of the University of Glasgow who was the senior author of a research poster presented at the meeting. He and his colleagues look at the relationship between systemic inflammation and prostate cancer survival. Since there is some evidence that pre-treatment of systemic inflammation in men may be associated with [...]

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