Dr. Steve Freedland, from Cedar Sinai conducted a controlled, randomized clinical study that evaluated the efficacy of an extremely low carbohydrate diet on the side effects of hormone therapy (ADT). The study showed that an extreme diet has a positive impact on many of the side negative effects as well as causing significant weight loss [...]
One of the newer drugs and one that has recently had great air play is the bone targeting radiopharmaceutical drug radium-223 or Xofigo. Currently, it is approved for men with castrate resistant prostate cancer with bone metastases. The problem is that currently Xofigo is only approved for one round of treatment using 6 monthly infusions. [...]
Prostate cancer tends to metastasize to bones as opposed to soft tissue and other organs. We have no idea why it does have a preference for bone, but it does. Developing bone metastases in prostrate cancer is a very strong negative prognostic indicator. Prostate cancer’s tendency to favor bone over soft tissue causes significant morbidity [...]
There are many different types of drugs used for hormone therapy in the treatment of prostate cancer. One of the newer classes of drugs include the GnRH antagonists. Degarelix (aka Firmagon) is the one drug in this class that is currently approved for prostate cancer. Degarelix, like the other hormone therapy drugs, was developed to [...]
Malecare launches Cancergraph, a Quality of Life mobile app recording. It's free on the iOS Apple App store, right now! Go to the App store on your iPhone or Download here https://itunes.apple.com/us/app/cancergraph/id1114343314?mt=8 Android coming in November. Cancergraph tracks your cancer symptoms and side effects over days, months and years. Designed by cancer survivors and caregivers, [...]
Chemotherapy with Taxotere (docetaxel) might not be considered because the side effects are misunderstood. Individual experiences and side effects differ widely from one man to another. n Generally, chemotherapy is not as toxic as we think. Even if a patient feels that his chemotherapy is causing more grief than relief, it can be discontinued; there [...]
We know that men with metastatic castration-resistant prostate cancer (mCRPC) and visceral metastases have a worse prognosis than those with non-visceral metastases. The important question we need to understand is what, of our currently available treatments, might be effective for this more aggressive and deadly type of prostate cancer? Results of the phase 3 AFFIRM [...]
Malecare's Founder and Executive Director Darryl Mitteldorf was this years PCRI winner of the Harry Pinchot Award. He is long deserving of this award. I would like to thank Darryl for his years and years of work and PCRI for recognizing his major contributions to our prostate cancer community. Thank you Darryl A video of [...]
Clinical trials are the main stream of developing and then getting necessary approvals for drugs to be able to make it to market. Drug companies, like every other company and every individual want only to have successes. We all also have egos and when there is a failure we often prefer to bury that information [...]
Peripheral neuropathy caused by chemotherapy is a very common problem for many of us as we go through a chemotherapy regime. Despite the large numbers of us who do suffer from this side effect there has been limited numbers of doctor suggested remedies. On the Malecare/ HealthUnlocked Advanced Prostate Cancer online support group there was [...]
