pain | malecare.org

The PREVAIL Trial Shows That Enzalutamide Not Only Increases Overall Survival Over Placebo, It Also Delays the Onset Of The First Skeletal Event

Analysis of the PREVAIL Trial showed that Enzalutamide (Xtandi) significantly increased overall survival and radiographic progression-free survival compared with placebo in men with prostate cancer who were asymptomatic and minimally symptomatic, chemotherapy-naive and who had metastatic castration-resistant prostate cancer (mCRPC). Now, an additional analysis of the data has shown the effect enzalutamide also has on [...]

By Malecare|2020-02-04T11:37:24-05:00May 22nd, 2015|Advanced Prostate Cancer, Bones and Prostate Cancer, Clinical Trials, enzalutamide, Quality of Life, survival, Uncategorized, Xtandi|0 Comments

Pain and Its Under-Treatment in Advanced Cancers

I really thought we had gotten over this problem, but an article appearing in a recent report in the Journal of Clinical Oncology indicates that the age old problem that often our doctors fail to supply adequate pain medications to advanced cancer survivors because a fear of drug addiction This attitude still hampers good survivorship [...]

By Malecare|2017-10-19T10:48:03-04:00September 8th, 2014|Advanced Prostate Cancer, ASCO, Bone Metastases, Drugs & Treatments, Pain, survivorship, Uncategorized, Understanding APC|0 Comments

Denosumab is Superior to Zoledronic Acid (ZA) for Pain Interference and Quality of Life

Men with castration-resistant prostate cancer (CRPC) and bone metastases (BM) will eventually develop debilitating pain that impacts daily functioning and diminishes their quality of life. Based on prior studies, including a phase III trial, the superiority of denosumab over zoledronic acid (ZA) in delaying or preventing skeletal-related events (pathological fracture, radiation or surgery to the [...]

By Malecare|2020-02-04T10:22:05-05:00May 27th, 2014|Advanced Prostate Cancer, Bone Health, Bone Metastases, denosumab - Xgeva, Drugs & Treatments, Quality of Life, Uncategorized, Understanding APC, Zometa|0 Comments

Denosumab or Zoledronic Acid – Which is Superior for Pain Interference and Improving Quality of Life?

Men with castration-resistant prostate cancer (CRPC) and bone metastases (BM) will often have debilitating pain that impacts every aspect of their daily functioning thus significantly diminishing their quality of life (QoL). Finding the best drug or treatment to control the pain will allow men to have a more complete and fulfilling life as well as [...]

By Malecare|2014-04-24T12:38:13-04:00April 24th, 2014|Advanced Prostate Cancer, bisphosphonates, Bone Health, Bone Metastases, denosumab - Xgeva, Drugs & Treatments, Pain, Uncategorized, Understanding APC, Zometa|0 Comments

CAUTION – PAIN PATCHES (FENTANYL) CAN CAUSE A DANGEROUS OVERDOSE

Leslie from the Malecare Advanced Prostate Cancer On-line Support Group made a post today warning us that there have been significant malfunctions in fentanyl patches. Fentanyl patches are used to control severe pain, especially in men with very progressed advanced prostate cancer. According to the information posted some of these patches are malfunctioning causing accidental [...]

By Malecare|2021-02-17T10:21:12-05:00January 9th, 2012|Advanced Prostate Cancer, Drugs & Treatments, Pain, Uncategorized, Understanding APC|1 Comment