I now have some additional information about the Early/Expanded Access Program for Enzalutamide (MDV-3100)for men with advanced prostate cancer. Jan Manarite, who is a member of the Early Access Committee has provided the following information:

From the Early/Expanded Access Committee – Now available in 10 states (see list below in this post) with additional states anticipated in the near future.

The goal of the access program is to provide expanded access to MDV3100 and to monitor its safety in men with progressive castration-resistant advanced prostate cancer previously treated With docetaxel based chemotherapy. In this trial there will be no placebo and no cost for MDV3100 (check with trial site for any other costs).

Basic Eligibility Criteria:

CRPC/HRPC – on hormone therapy with progressive disease
Metastatic advanced prostate cancer
NO small cell or neuroendocrine features
Previously treated with Taxotere (docetaxel)
No brain metastases
HGB 9.0 or higher
No history of stroke or seizure
No significant cardiovascular disease

If you think you fit the above Criteria, contact one of the sites below for further criteria and screening.



Alaska Clinical Research Center, LLC
Contact: Robin Adams (907) 276-1455
Anchorage, Alaska 99508


Pinnacle Oncology/Hematology
Contact: Sherril Bierman (480) 278-8804
Scottsdale, AZ 85258


Prostate Oncology Specialists
Contact: Jennifer Leung (310) 827-7707
Marina del Rey, CA 90292

Dr Ronald Yanagihara
Contact: Katrina or Lara (408) 847-6194
Gilroy, CA 95020


Investigative Clinical Research of Indiana LLC
Contact: Leslie Weitman (317) 716-0323
Indianapolis, IN, 46260


Jackson Oncology Associates, PLLC
Contact: Teresa Davis (601) 974-5547
Jackson, Mississippi, 39202

    New Hampshire

New Hampshire Oncology Hematology PA
Contact: Margaret White (603) 224-2556 x 1323
Hooksett, New Hampshire, 03106

    New York

Accumed Research Associates
Contact: Tammi Allegra (516) 746-2190
Garden City, New York, 11530

    North Carolina

Cancer Centers of North Carolina
Contact: Julia Berry (919) 781-7070
Raleigh, North Carolina, 27607

    South Carolina

Charleston Hematology Oncology Associates, PA
Contact: Deborah McNeal (843) 266-2540
Charleston, South Carolina, 29414
Carolina Urologic Research Center

Contact: Tabitha Joyner (843) 449-1010 x228
Myrtle Beach, South Carolina, 29572


Virginia Oncology Associates
Contact: Wendi Gobhardt (757) 213-5813
Norfolk, VA, 23502

* Enrollment Tip – ?It often takes a few weeks to complete the enrollment and screening process for an expanded access trial. You may be able to speed up this process by supplying the clinical trial nurse with your own medical records, which may relieve him/her from trying to obtain them from another clinic. Factor all of this into your decisions. As always, discuss with your physician(s).

Joel T Nowak, M.A., M.S.W.