ADJUVANT AND SALVAGE RADIOTHERAPY AFTER PROSTATECTOMY: NEW ASTRO/AUA GUIDELINE

A joint task force composed of members from the American Urological Association (AUA) and the American Society for Radiation Oncology (ASTRO) has presented formal guidelines for the use of adjuvant and salvage radiation after a radical prostatectomy. To construct the Guideline they relied on a systematic review of the literature using the Pubmed, Embase and [...]

The AUA Issues Specific Guidelines for the Treatment of Men with Castrate Resistant Prostate Cancer

There was a lot of interesting and important presentations at the recent American Urological Association meeting, however the one item that will have the most impact on men with advanced prostate cancer is the new guidelines that were proposed for the treatment of men with castrate resistant prostate cancer. The guidelines were organized by creating [...]

Statin Use And Better Prostate Cancer Outcomes

Not approved, not even tested with an appropriate clinical trial, but research has again shown that the use of statins in men with prostate cancer may have a lower risk of dying from the cancer than those who do not. In a study of 1,001 prostate cancer patients who were diagnosed between 2002 and 2005, [...]

Large Data Analysis Finds That Intermittent Hormone Therapy Is Equal to Continuous Therapy for Men Who Are Good Initial Responders

The Journal of Clinical Oncology, published an article by Niraula et al. that searched the general literature published through August 2012. They searched MEDLINE, EMBASE, the Cochrane Library, as well as most major conference proceedings. Their criteria for inclusion included randomized, controlled trials of intermittent hormone therapy (IADT) as compared to continuous hormone therapy (CADT) [...]

Teleconference – A New PROSPECT for Prostate Cancer Patients this Tuesday at 6 p.m.

Malecare will be holding a free teleconference this Tuesday, April 30 at 6.m. I will be speaking with Dr. James Gulley who is the Deputy Chief of the Laboratory of Tumor Immunology and Biology at the National Cancer Institute and the Director of the Clinical Trials Group. He also serves as a Senior Investigator within [...]

Why Prostate Cancer that is Hormone Resistant Still Responds to Hormone Manipulation

I don’t understand why if I have hormone resistant advanced prostate cancer why the new drugs, Zytiga and Xtandi work. These drugs are still hormone therapies, is my prostate cancer hormone resistant? I recently received an email asking me this question and I thought it might be a question many people have, so I am [...]

Confronting The Terror in Boston – What It Could Mean for Us

We all know about the terror that has struck Boston. Two bombs exploded near at the finish line of the Boston Marathon, killing three people and seriously injuring over 150 other individuals! One of the dead was an eight-year-old child. I know when I heard about the death of the child I prayed that this [...]

An Alternative to Radiation for Pain Relief Of Painful Bone And Soft-Tissue Tumors – Microwave Ablation

Currently as our advanced prostate cancer progresses and we develop bone and soft tissue tumors our pain increases significantly. Current treatment options for the palliation of this pain includes painkillers (including opioids and methadone), radiation and in rare incidents surgery. All of these options have significant limitations. Drugs eventually become less effective, especially for breakout [...]

Barvarian Nordic Provides A Long Anticipated Update on Their Randomized Phase 3 trial of Prostvac VF

Barvarian Nordic (BN) released some outstanding news a few days ago. According to BN they hope to complete the enrollment in their phase 3, double blind, randomized, placebo controlled, international clinical trial of their cancer vaccine, Prostvac VF. The trial known as PROSPECT is scheduled to be completed with in the next 12 months, unless [...]

Prognostic Significance of the PSA Nadir Level after ADT for Prostate Cancer

Having your advanced prostate cancer progress to becoming castrate resistant is a major moment in our life. For many of us becoming castrate resistant signals a major change, a foreshadowing of what the future holds. Becoming castrate resistant heralds our eventual decline which can only lead us to one destination, our demise. How long it [...]

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