Having your advanced prostate cancer progress to becoming castrate resistant is a major moment in our life. For many of us becoming castrate resistant signals a major change, a foreshadowing of what the future holds. Becoming castrate resistant heralds our eventual decline which can only lead us to one destination, our demise.

How long it will take to reach the end remains very much an unknown. For some of us it could be less than one year and for others we can still be alive in 10 or more years. Like for anyone on the journey of life, there remain many unknowns, however when we become castrate resistant we know that we have taken an additional and significant step on the journey.

There has been s study that looked at prostate specific antigen (PSA) levels and the nadir (lowest number) after hormone therapy (ADT) and its potential to predict the progression to castrate resistance.

Researchers at the Department of Urology, Seoul National University College of Medicine and Clinical Research Institute, Seoul National University Hospital, Seoul, Korea studied the overall survival rate, incidence of progression to the development of castrate resistant prostate cancer and interval until progression were analyzed with reference to the nadir PSA level.

They reviewed the progressive status and survival of 177 men with stage