How to Manage the Side Effects of Hormone Therapy (ADT) in the Treatment of Prostate Cancer

David P. Wood, Jr., MD gave a presentation at the 9th International Prostate Forum (IPF) on October 8 - 10, 2009 in Izmir, Turkey on the Management the side effects of hormone therapy (ADT) when used to treat of prostate cancer. Dr. Wood indicated that the three major side effects of ADT in the treatment [...]

Does ADT3 Work for Men with A Biochemical Prostate Cancer Recurrence?

One of the most heated debates in prostate cancer care is around the use of 5-reductase inhibitors (5ARI) like Dutasteride as a third component of a hormone blockade (ADT3). 5-ARIs block the conversion of testosterone to dihydrotestosterone (DHT). DHT is thought to be an extremely powerful “fuel” for the growth of prostate cancer. However, there [...]

Effects of Denosumab on Bone Mineral Density in Men Receiving ADT for Prostate Cancer

The relatively new drug, denosumab, has proven itself very effective for men on a hormone blockade (ADT). In a recently completed 3-year, randomized, double-blind study at the Massachusetts General Hospital Cancer Center, Boston, Massachusetts, denosumab significantly increased bone mineral density and decreased new vertebral fractures in men receiving ADT for the treatment of advanced prostate [...]

Scott Goodwin Checks In

Scott Goodwin who periodically has been writing about his journey taking chemotherapy has given us a very moving update. Sadly, Scott is not doing well physically, but he is continuing his valiant fight against this insipid disease. - JTN I thought I would send a much overdue update on my progress with chemo, etc. I [...]

Time to Biochemical Failure and PSADT As Prognosticators To Metastatic Disease

A known fact is that between 15% to 35% of men who have surgery as their primary treatment after diagnosis of prostate cancer will experience a biochemical recurrence (BCR). The authors of a presentation, Michael B. Williams, MD, et al. presented at the American Urological Association Mid-Atlantic Section - 67th Annual Meeting - October 1 [...]

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