Apalutamide Looking Good as Treatment for Non-Metastatic Castrate Resistant Prostate Cancer

/, Clinical Trials, Clinical Trials, Hormone Therapy, Research, Understanding APC/Apalutamide Looking Good as Treatment for Non-Metastatic Castrate Resistant Prostate Cancer

Non-Metastatic Castrate Resistant Prostate Cancer (nmCRPC)  usually leads to metastatic prostate cancer and death. There are no approved treatments for nmCRPC. Apalutamide is a taken-by-mouth androgen receptor inhibitor with antitumor activity in CRPC. There’s a much talked and written about clinical trial called, SPARTAN, that investigated how well Apalutamide works on maintaining metastasis-free survival (MFS) in men with nmCRPC.  1207 participated in this trial.  pts were randomized. Apalutamide decreased the risk of distant metastasis or death by 72% , with a median metastatic free survival period of 40.5 (given Apalutamide) vs 16.2 months (control group not given Apalutamide). Apalutamide significantly improved median metastatic free survival by 2 years in men with nmCRPC. These results support using Apalutamide  in men with nmCRPC.

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Malecare is the world's leading men's cancer support and advocacy nonprofit organization.

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