When I had my recurrence in December of 2005, my PSA made it’s way to 87.7 and I had a PSA doubling time of 4.2 months. Hormone deprivation therapy (ADT) caused the PSA to “drop like a rock” and within six to eight weeks my PSA was happily <0.04 (undetectable). Things could not have progressed any better.After ten months, because of the very harsh side effects I experienced, which I have already described in this blog, I elected, against medical advice, to stop the hormone treatment, to go intermittent. When I decided to stop the treatment I anticipated having nine to ten months before I would have to go back and again start ADT. Needless to say I was not happy with that possibility of having to return to ADT, but I had decided that I would “bite the bullet” and recommence ADT at the appropriate time.Since stopping the therapy I have managed to stay off the drugs for 32 months and I am still counting, an unexpected long period of time. As of my last PSA test my level is still only at 0.40 (as of July 1, 2009). I celebrate this low number. My doubling time is about 5.36 months, longer than the doubling time of 4.2 months I experienced at the time of the recurrence.I often think about why the doubling time has gotten so longer (a 25% chage). The bottom line is that I don’t know and will never know. But I am willing to share what I have done with diet and supplements, my only currently active treatment. I have no way to know if this is the reason I have experienced a slowing down of the PSA velocity, but it is the only things I can think might have contributed to the situation.1- Maybe having been on ADT for nine months managed to kill off the more aggressive cancer cells, leaving behind only the less aggressive cells which just grow at a slower rate.2- I continue to take anti-inflammatory medications for an arthritic condition, but I was also taking these drugs at the time of the recurrence. These drugs include; sulfasalazine, sulindac, folic acid, and methotrexate. They definitely combat inflammation which I believe encourages prostate cancer cell growth.3- I now take a number of supplements that I was not taking until I had the recurrence. They include; vitamin D3 (1,000 iu/day), pomegranate (Pom Wonderful), vitamine C (2,000 mg/day) and green tea extract.Clearly something has changed, but I do not know what has caused the slowing down of the PSA velocity. I just thought I would share this information even though none of it may explain the positive change I have experienced.Joel T Nowak MA, MSW