The Role of PSA Kinetics in Men with Advanced Prostate Cancer

For men with metastatic prostate cancer, understanding ones prostate specific antigen (PSA) kinetics is important.  Despite the issues we hear  surrounding the PSA, it is still the best measure you have in aiding you in the assessing your possible outcome prognosis.  PSA kinetics also are a potential surrogate marker for  clinical trial results. In most [...]

By |2017-10-19T10:46:54-04:00October 14th, 2015|Advanced Prostate Cancer, Uncategorized|0 Comments

Impact of Postoperative PSA Scores on Recurrence and the use of Salvage Therapy on the Risk of Death

In a study conducted by Choueiri et al. published in Cancer it was suggested that men who have prostate cancer that was treated by a radical prostatectomy (RP) who then had a long time to a biochemical recurrence (BCR) or a long PSA doubling time after a BCR have no higher overall risk of death [...]

Changes of PSA Doubling Time is Associated with Disease Progression in Men with Biochemically Relapsed Prostate Cancer Treated with Intermittent Androgen Deprivation

Researchers at the The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland studied the relationship between the change of PSA doubling time (PSADT) and disease progression during intermittent androgen deprivation (IAD) therapy for prostate cancer. They retrospectively analyzed the data from 96 men diagnosed with biochemically relapsed prostate cancer (BRPC) who [...]

Pomegranate and Its Role In PSA Velocity

In 2005 there was a small clinical trial performed at UCLA evaluating pomegranate juice and its ability to control PSA for men with prostate cancer. The trial gave 8 oz. of POM Wonderful pomegranate juice each day in men with a rising PSA post treatment (recurrent advanced prostate cancer). This trial, which was funded by [...]

Finasteride Extends PSA Doubling Time & Reduces the Rate of PSA Increase

Finasteride, which remains a controversial drug in the treatment of men with advanced prostate cancer, prolongs the time of off-treatment in men with advanced prostate cancer when they are using intermittent androgen suppression therapy (IAD). One of the questions not yet understood is whether this results from a true increase in prostate-specific antigen (PSA) doubling [...]

Pomegranate Juice May Slow the Progression of Post-Treatment Prostate Cancer Recurrence

When your PSA starts to rise after you have received primary treatment you need to be concerned that your prostate cancer has reoccurred. The first indicator of recurrent prostate cancer is a detectable level of prostate-specific antigen (PSA). Research has demonstrated that PSA doubling time is a reliable tool to distinguish which cancers pose a [...]