Sanofi-aventis, the pharmaceutical company that makes taxotere and the newly approved drug, Jevtana (cabazitaxel) yesterday announced that their newly approved treatment for men with metastatic hormone-refractory prostate cancer (mHRPC) who have been previously treated with a docetaxel-based treatment regimen and failed is finally available for distribution in the United States. Around one month ago, Jevtana was approved by the U.S. Food and Drug Administration (FDA), but it has not been available.
Jevtana which is used in combination with prednisone was approved by the FDA based on results from the Phase 3 TROPIC clinical study which involved 755 patients with mHRPC previously treated with a docetaxel-containing treatment regimen. Results from this trial demonstrated:
* a statistically significant 30%
• Neutropenic deaths have been reported. In order to monitor the occurrence of neutropenia, frequent blood cell counts should be performed on all patients receiving JEVTANA®. JEVTANA® should not be given to patients with neutrophil counts of ?1,500 cells/mm3.
• Severe hypersensitivity reactions can occur and may include generalized rash/erythema, hypotension and bronchospasm. Severe hypersensitivity reactions require immediate discontinuation of the JEVTANA® infusion and administration of appropriate therapy. Patients should receive premedication.
• JEVTANA® must not be given to patients who have a history of severe hypersensitivity reactions to JEVTANA® or to other drugs formulated with polysorbate 80.
The information in this post was supplied directly from Sanofi-aventis.
Joel T Nowak, MA, MSW
Hi …how & from where can I get Jevtana in India? What is the projected cost per cycle(course) & how many cycles one has to take for completion of treatment.
I do not know if Jevtana is available in India. I would go to their web site and contact them directly.
Just wondering if you have been able to find out when Cabazitaxel will be available in India ?
what will be the cost per dose of JEVTANA® (cabazitaxel) in U.S. ? AND FROM WERE IT WILL BE AVAILABLE ? contact me fast as possible….
Prices do vary, but I have heard that one year of treatment in the United States can cost as much as $93,000. – Joel
Grace, I do not believe that this has been approved in India. I believe the only place to get it today is in the United States. – Joel
how can i get this medicine in India.and what would be the cost,
how may inj has to be taken.
It is not approved in India. – Joel
Hey, believe jevtana is available in india now, starting last week. dont know the cost. let me know of the cost, if anyone is aware..
Where ca i find this drug in Chile ? i need just two dosis of it. Which is the price of it.
I do not believe that it has been approved in Chile.
I am writing from Turkey. Do you have using this medication and result in? If users sevinirim information. My father used a second dose now. Most side effects seen in the specified. will take two doses. How many doses would be useful if?
Today my grand father has been injected jevtana at Fortis hospital, Amritsar. He is having prostate cancer. The cost of one dose is 2,20,000. As we are getting a complimantory dose with every two doses. The mrp writen on the box was 3,30,000. So we r getting three doses at Rs.660000. Also you have to buy Pegasta 6mg with every dose. Contact me at 9988942608 for any other details. Thank you.
Today my father has been injected jevtana at MP SHAH CANCER hospital, AHMEDABAD. He is having prostate cancer. The cost of one dose is 2,20,000. As we are getting a complimantory dose with every two doses. The mrp writen on the box was 3,30,000. So we r getting three doses at Rs.660000. Also you have to buy Pegasta 6mg with every dose. Contact me at 9904580520 for any other details. Thank you.
my brother aged 76,diagnosed ca prostate 6 years back,orcidectomy done,already had doctaxel,honvan inj,3 months abiterone .now psa 42 ,bone scan normal ,one doc advised zevtana .we gave first injection but so many side effects what should we do
Ask your doctor about Zytiga. – Joel
Hi, My Papa is suffering from advanced prostate CA with bone metastases. He goes through unbearable pain and is unable to walk or sit or stand for long. We have given him 2 cycles of Docetaxel and 1 fraction of radiation on right pelvic bone including proximal femur. His pain has reduced on the area where radiation was given however both his legs and back have severe pain. What should I do to improve his quality of life and how long can he survive? What other treatment options are available?
First. I am sorry to hear about your Papa. I don’t know where you live because the availability of treatments varies from one country to the next. I also don’t know what other treatments he has had. Pain is always diffic