How I Became The “Trimix Lady”

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Folks, on August 13th I’ll be celebrating my first anniversary of participating in online conversation.  It also happens to be my birthday.   

When I initially posted to a bulletin board I was looking to spread the gospel of penile injections for ED, and I thought that would be the end of it. 

My husband had had an RP about 10 months before (Oct. 15, ’05), and since then we had not had “normal sex”.  We were advised to learn to “use our bodies in different ways”.  Easier said than done.   I did learn to French-kiss at forty-something, but things just weren’t the same. 

Also, your mother doesn’t teach you how to, uh . . . manually stimulate a man.  And “Ol’ Man River” must have surely known somethin,’ but he “didn’t say nothin’  (as usual).  So I had to learn by trial and error. 

I was stroking his penis in largo, e.g., slow and gentle, but I eventually learned that it only worked if I speeded up the tempo and the pressure,  do it in allegro vivace,  maybe.

Eventually we found a top-notch ED doctor who gave dear husband an injectible potion called Trimix.  Like all guys, DH was not exactly keen on shooting up *there*.  But after Dr. Melman gave him the first shot, his fears vanished.  (He says to tell all you guys that it can be done.  Don’t give up.)

Now this was SEX!!!  Better than the real thing.  Erections came in XL and above only.  I am sure for a guy who hadn’t “seen action” down there in almost a year, this was a most welcome sight.  And with Trimix *you* are in control.  Just like with the Tempur-pedic bed, *you* set the firmness.  And the pace.  You can go on forever as long as time is no object. 

Our first session with the elixir was proceeding at a leisurely pace when I happened to glance at the clock.  I noticed it was coming up on an hour.  I was getting a little tired, but being the competitive type I decided to go for a record — I held out for exactly an hour and a minute.   Then I collapsed.  Boy, did I need a drink and a Power Bar!  But that was just a “dry run.” 

I must tell you, dear readers, that if you take a breather, a “seventh-inning stretch” so to speak, you *can* even have a “double-header”.  If you so desire.

Anyway, them came August 13, my birthday, and DH got me a beautiful bouquet of flowers.  Monochromatic, pink and purple tones.  Exquisite.  I am a “flower child” in the sense that there is nothing I love more in the world than some pretty blossoms.

That same day DH went off to Vermont on a bike trip, and I became the “Trimix lady”.  I had never had an interest in online conversation, but I felt I had an almost sacred duty to tell the world about this miracle cure for ED.  So I rhapsodized a bit about it in alt.impotence and  I thought this would be a one-time thing.  But then I got some nice notes from people in the groups (as well as some propositions), and I became hooked on prostate cancer conversation.

The biggest problem with injections for ED is that men are very put off by the prospect of “shooting up” there.  But these fears can be overcome.   After dear husband’s first shot at the doctor’s office, his fears went away.

Also, injections have been shown to play a role in “penile rehabilitation,” or restoring natural erectile function after surgery.  Other methods have *not been proven* to do this.  I have been researching and speaking out about penile rehab for almost a year, and this is something I will definitely be focusing on here.

Like everything, injections have a downside.  You have to be sure to do it on both sides of the penis.  Or you can end up with a “Leaning Tower of Penis.”

I just wrote to someone that Trimix could give an erection to a corpse who was doing his taxes:-))

Next article: Pump and Circumstance 

By | 2007-07-27T15:20:58+00:00 July 27th, 2007|For Partners, Penile Rehabilitation, Sexuality and Intimacy|35 Comments

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  1. Eric Sondeen July 27, 2007 at 4:33 pm

    Leah: I appreciate your candor and Old Man River’s willingness to share your “findings”. This adventure of PCa is all over the board and only by sharing our discoveries as patients and families can the whole, holistic, and quality of life story be pieced together. Thanks for the contribution of your couple’s journey–shared.

  2. Tom Rue July 29, 2007 at 7:24 am

    Leah, your posts are always informative, insightful, and a pleasant read. Happy “first anniversary” — which I trust you and Ted will celebrate well. Thanks to both of you for your openness in sharing what you’ve learned.

  3. Marge Dargahi July 31, 2007 at 4:37 pm

    I was referred to your blog from the Circle and I’m so glad to have found you. We all need some humor, but I also feel your warmth and your wisdom. I will be a regular from now on. Thank you.

  4. Ben September 16, 2008 at 8:06 am

    Just started trimix since my rrp 3mo ago, and yes sure dose work, still alittle apprehension with the needle, but that is nothing when you begin to feel the surge feeling as you start to inflate, 🙂 and even tho there is no fluid during orgasm, it’s a prolonged orgasm, great feeling,, i would like to hear from some other users, and your thoughts. thanks

  5. Curt July 20, 2009 at 6:48 pm

    Two years ago, looking for an alternative to Viagra, whose side effects (headache, blocked sinuses, nasty stiff neck, general ill feeling) were increasingly annoying, I discussed the issue with my urologist who recommended TriMix. Once past the initial apprehension of sticking a needle in Mr. Happy (a very easy transition since it is an easily tolerable minor prick, if you’ll excuse the choice of words), I have, at the age of 67, become an evangelist for the drug. Using it at least 5 times a week (my wife is, shall we say, very energetic when it comes to sex), it is, as my doctor says, truly the “Wonder Shot”. Instant, long lasting, no side effects. Just incredible. Anyone who suffers from ED, is looking for a solution, and doesn’t explore this wonderful alternative is doing themselves a great disservice.

  6. Ernie September 4, 2009 at 11:40 pm

    What is the typical formula of trimix?

  7. Leah September 5, 2009 at 12:52 pm

    I believe it is papaverine, phentolamine and alprostadil (prostaglandin). If you want to learn more about this subject, I suggest you join the prostate pointers mailing list “PC and Intimacy”. Can’t recommend it enough.

    They also have their own “wiki” where they store information for reference.


  8. Angeline December 6, 2009 at 11:37 pm

    Wow, your info is changing how I look at things. My husband is reluctant, but at least he knows how important this is to me. At first, I was disheartened that it isn’t THAT important to him, but I think the shot thing has him spooked.

    In any case, things are getting better since I read your information. I thought it was “all over” but am finding out that just isn’t so. I’m looking forward to us getting better and better now that I found this website.

    Thank you so much, you can’t imagine how much you’ve helped people.

  9. Not having sex April 21, 2010 at 3:36 am

    This is not working for my husband, he has three bottles frozen and we are not having sex. Is he cheating or what?

  10. Chuck Weidman August 2, 2010 at 12:06 am

    It is stated to NOT freeze these hormones on the instructions as such will destroy the effect. Also, good info but my urologist says one should wait 48 hours between injections…is that necessary?

  11. Steve May 21, 2011 at 1:36 pm

    Had surgery for prostrate cancer on 2/17/11. Dr prescribed Trimix in April. Used
    5 cc nothing happened. Next night used 10 cc it was ok. Very sore took 1.5 hrs to go down. Next time used 10 cc again nothing happened. A little sore.
    Jumped to 12 cc had a great time but erection lasted 2 hours and very sore. Took 2 extra strength Tylenol , 2 sudafed and ice. Did not help.
    Dr doesn’t want to change mixture. Wants me to try 10 cc again or go to 11 if 10 doesn’t work. Is trail and error normal? Is extreme soreness and two hour erection normal? I’m only 61.

  12. Leah June 14, 2011 at 12:52 pm

    Dear Steve,

    As you know, I am not a doctor. But I can tell you that trial and error is normal with Trimix. You eventually learn to “titrate the dose”, which is just a fancy word for getting it right. And yes, you can have soreness, but it’s not normal. My husband had it once and he was pretty unhappy. Yes, you can have long erections with Trimix. Once, my husband was just about hitting the 4-hour mark, you know when you’re supposed to go to the ER. Try NOT to have longer erections because this can damage the penile tissue.

    I suggest that you join the group called “PC and intimacy”. There are people in the group who are very knowledgeabe about this subject, although, like me, they are not docs.


  13. tim cassia June 24, 2011 at 9:48 pm

    For those of you haveing little luck with the trimix there is a Qudmix they just added atropine to the mix..

  14. Dixon Brandt June 27, 2011 at 10:44 am


    Your Doctor can have Lidocaine added to the Tri-Mix to reduce or eliminate the pain.

    I experienced this problem and Lidocaine was the solution.


  15. john boman July 21, 2011 at 6:13 am

    Hi Leah ,
    I had a radical prostatectomy in March this year , was 66 in June and in the same month my wife and me passed our 41 anniversary .Phew ! Medals ?
    I am in UK ,where our health system is different to yours.
    I would just like to pass on my thanks for your blog .I stumbled on it on Google but am relectant to say what words I used as a strap to ‘Google’ I found it amusing and informative but better than that, I found it encouraging .

    I had just received a phone call from my General Practioner to say they will NOT prescribe the cialis that my consultant ( we refer to specialist sugeon as ‘our consultant ‘ ) had prescribed might help my/our problem.
    Well done you ….and kind regards to you and your husband. Thanks

  16. john boman July 21, 2011 at 6:16 am

    Hi Leah ,
    I had a radical prostatectomy in March this year , was 66 in June and in the same month my wife and me passed our 41 anniversary .Phew ! Medals ?
    I am in UK ,where our health system is different to yours.
    I would just like to pass on my thanks for your blog .I stumbled on it on Google but am reluctant to say what words I used as a strap to ‘Google’ I found it amusing and informative but better than that, I found it encouraging .

    I had just received a phone call from my General Practioner to say they will NOT prescribe the cialis that my consultant ( we refer to specialist sugeon as ‘our consultant ‘ ) had prescribed might help my/our problem.
    Well done you ….and kind regards to you and your husband. Thanks

  17. Ted Shokes December 14, 2011 at 10:03 pm

    I haven’t had prostrate surgery or such; but am impotent due to blood pressure and anti depressives. I’m 61 and pills (Viagra, Levitra, Cealis, etc worked for awhile but eventually became ineffective). I’d given up on having a sex life, which is sad at 61 and sadder if you’re wife is 39 and has a libido that doesn’t have an “off” switch. Anyway, our marriage suffered because we had to make so many compromises to keep things going (I’ll not go into detail but some are considered “not mainstream”). Got the “tip” on trimix from my younger diabetic brother who nagged the hell out of me to give it a try. Yeh, I’ll try it, but the “needle thing” was really my big hang up. Anyway, I got a urologist who thought it was a swell idea. Showed me everything about the injection (got one) and everything was hunky Dory. Since I had little reaction to 15 units, he suggested I go up by 10 units (25) for my trial run with wife. Well, I took 30; close to 25 right? And had amazing sex with my wife for the first time in about 10 years. It was great! I went to sleep after almost 2 solid hours of mind blowing sex. Big mistake. Woke up with priaprisim and wound up in ER. Such fun! Not deterred, and having to wait almost a month to heal (believe me guys it’s no fun). I tried again, 15 units this time and bang! It worked again. Still the erection lasted almost 6 hours before relenting. Moral of story, don’t fall asleep if you still have an erection and listen to Leah. There is trial and error with trimix and dosage, but once you get the “sweet spot”; your life will change.

  18. wildman January 17, 2012 at 4:10 am

    This is in response to Steve, May 21, 2011, just to clarify. Surely you are not taking 10-12 cc of tri-mix! I use 0.4 cc & Doc says I could go up to 0.9 & then, he would suggest a different “blend”. There is some trial & error involved. I have erections that last a couple of hours, depending on stimulation.

  19. David April 3, 2012 at 10:09 pm

    A friend of mine runs some of the Male Performance Clinics in TX introduced me to TRIMIX about 6 months ago and I can not be thankful enough,, It was a little nerve wrecking at first but after about the 7th time of injecting myself I have no hesitations about the process, It did not take long to get my doses correct so that I do not need antidote any more. that took about 2 weeks and I use every two days. I am starting to get natural erections almost every morning and threw out the day. I prefer the semi auto injector to the fully auto because I inject low on one side and higher on the other side of my penis. which makes my penis bigger in girth and it just seems to work better for me.and the girth is there now with my natural erections.I had no problems jumping feet first into this great thing and any man who has a healthy apatite for sex should not be afraid and jump in and please there lady’s,, they wont stop smiling!!! FYI,,,I have at least for myself, if you hafta knock it down a worm or hot shower or bath will do it and if not your mix needs to be adjusted. I had to adjust mine several times in the first few weeks,, I think my member forgot what it was like to stand up strait at first but not any more. I would like to thank the great staff Doctors and my good friend at The Men’s Performance Center In Cow Town FT Worth TX.

  20. Chris May 28, 2012 at 7:26 pm

    i am a 42yr old type 1 diabetic. though my condition is different from what i have read here, i share a side effect. my ED became an issue as i grew older till about 4yrs ago it stopped functioning all together. combined with PE this made intercourse a distant dream. i had tried oral medications which worked for a short time and after they stopped working i had all but given up. a yr ago i heard a commercial on the radio for a doctor here in FL that guaranteed success or your money back. as a corner store clerk it was 6 months before i had the free capital, $200, to make the appointment. After they checked for blood flow they gave me a test injection. a few minutes latter they checked on me for results. though i felt like it had no effect they claimed i had a 90% reaction to the test injection. they immediately went into the sales pitch for trimix and a auto injector. the trimix $145 for 5 doses and $195 for the auto injector. By this time i felt they maybe taking advantage of men with ED and left without purchasing either. after doing some research at home i discovered many pages like this one that claim trimix does work so 6 months later, last week, i called them up and ordered the 5 doses. its due to arrive this week and i cant wait to get with my wife for the first time in 4yrs. my question is $145 for 5 doses about normal and is there somewhere i can order an auto injector for less than the almost $200 they want.

  21. jerry May 29, 2012 at 1:36 pm

    My uro. waited a year before he gave great but the only problem is it mostly last to long. My frist injection given to me to take home was 30 units.It lasted 6+ hrs. had to go to ER. Next injection was 10 units it was 4 hrs,since then I have used 4 to 6 units worked ok 2 to 3hrs.Last week I used 6 units and it lasted almost 6hrs.headed ER.but released before I arived . This is my 4th month.Any suggestions

  22. paul September 23, 2012 at 9:56 am

    Thanks Trimix Lady,

    Having recently started using Trimix, I noticed after the second shot that I was able to perform fairly well between injections (5 cc) – I had been wondering about the rehabilitation aspect of what happened – nice to find out it is true. I also experienced some soreness – I will have to ask my urologist about the addition of licodaine. And I will have to remember to switch sides – the urologist never mentioned that one.

    The first time the urologist offered this to me 2 or 3 years ago my wife was against it – none of the pills worked – headache, stuffiness – I wish I had not waited so long to try it.

  23. paul September 23, 2012 at 10:03 am

    oops 0.5 cc

  24. George October 24, 2012 at 9:59 am

    Hi Guys, You need to seek professional help when using trimix. A urologist is a great start but they are not good enough. You need to go to an ED center that specializes in this. They will treat and adjust the medication so it works for you. We are located in Leawood, Kansas, Men’s Edge…913-553-4614. We are doing it right. We have over 300 formulations to work for you. Thanks….George

  25. del December 8, 2012 at 5:58 pm

    Tried trimix at different strengths before finding that I am one of the 7% of users for whom the effects are negated by Cymbalta (may also be surpressed by naproxen or ibuprofen– or other NSAIDS. So my choice is, sex or pain. Right now I am undecided. Feedback desired.

  26. G December 22, 2012 at 11:36 am

    Explain to people what a unit is, and what a mark on a 1cc syringe is.

    I see posts of 20 & 30 cc of tri-mix. I assume it is 20 or 30 units or 2/10 or 2/10 cc
    not actually 20 or 30 units of trimix.

    This misinformation can be dangerous to newbies.

  27. G December 22, 2012 at 11:38 am

    I see posts of 20 & 30 cc of tri-mix. I assume it is 20 or 30 units or 2/10 or 2/10 cc
    not actually 20 or 30 cc of trimix.

    Sorry I make the same mis-print or error.

  28. Tom December 28, 2012 at 10:54 am

    For you guys that have went to Mens Clinics and are paying outrageous prices for trimix, visit a urologist and have his write a prescrip for trimix, then take it to a Compounding Pharmacy. I get about 25 doese for $125, supplies inc.

  29. SueJean DeMinico January 15, 2013 at 9:52 pm

    Hi Leah,

    So happy there are women like you out there. My dear “boyfriend” (I am 61 and he is 66.. guess I should say partner or lover have used trimix for the last 4 yrs. He had his prostate removed in Jan. 2008. He had no problem getting used to it, as we both are pretty uninhibited and just wanted our old life back. It has been a Godsend. We love it. But, therein lies my question. The last 2 weeks, the needle does not seem to go in easily. It will bend, as if it’s hitting a hard spot. He tries several times to make it work, and is usually successful but that is frustrating to him, plus it has started to hurt him a bit. He’s going to the urologist tomorrow (the nurse practitioner there) to explain to her the problem. He uses 28 gauge needles, and the bottle of stuff has a different top on it, so we’re hoping it’s just a product, technical problem if you will. Anyway, if you have thoughts on what it could be, let me know. We are certainly not giving up! Best Wishes, SueJean

  30. Herbert February 12, 2013 at 10:13 pm

    Anyony know Dr. who will prescribe trimix in North Carolina? Thanks!

  31. Ken February 22, 2013 at 12:20 pm

    I scheduled for my first trial dosage in 3 weeks and I am scheduled to leave on vacation two days later. Is there any concern about that? If my erection does last too long do they have a way to reverse the Trimax effect or is it a trip to the ER? If it does cause a trip to the ER how long does any residual pain last? I am going to Mexico from Michigan so I dont want any issues to come up while in Mexico. The appointments are very difficult to get where I live.

  32. Ian s March 23, 2013 at 7:14 pm

    Hi, Has Radical Postectomy 14 months ago. Purchased a needle-free Injex unit for $300. tried trimix 30 then 50 units. Slight firming. bypassed the Mega trimix (double strength) to the Super Mega (double again) – Wow. aching and gone very bruised. as if the mix is either far too strong or gone to the wrong area. Injecting in areas 9-11 o’clock area and 1 to 3 o;clock area. Any other cases of this – still reluctant to try needle. Injex claims to penetrate to 0.9mm. It black and blue last 2 times sinc using the super strong trimix. Any thoughts?

  33. Ian s March 23, 2013 at 7:35 pm

    Thought the first time must have hit a vein but second time was sure to miss a vein but still aching heaps. Used 20 units (1/5 ml) got about 35% erection. Blown out in middle. Any advice is appreciated – Freezing both TriMix and Super Mega TriMix until I can find a way. Last resort is to us standard TriMix with needle.

  34. LovinTrimix November 16, 2013 at 2:35 pm

    47 year old Type 1 diabetic. ED for several years now. Tried all the oral medications with no success. I thought that implant surgery was my only option so I went to a urologist who introduced me to Trimix.

    I am now kicking myself for not going years ago. This stuff is wonderful! Don’t worry about the injections you’ll get over it its not really that big of a deal.

    the hardest part is trying to learn to have sex again. Although it is kind of like riding a bike you don’t really just have to learn that you no longer have to rush it. You don’t have to worry about finishing before anything goes away.

    if you suffer from ED go see a urologist. For years I just talked to my android can I adjust and my general physician and I should have gone straight to a specialist. Make the appointment right now, call them, you won’t regret it.

  35. John November 25, 2013 at 11:08 pm


    Thank you for taking the lead on this. As a man who has used both pill type enhancements and TRIMIX, I prefer TRIMIX as there are fewer side effects. For men, once they realize there are relatively few nerve endings on the shaft of the penis, it is really quite a painless procedure. I would like nothing more than for my partner to take an active role in the process, however women can be just as squeamish as men about any injection anywhere…especially there. Keep up the fight Leah and get the women involved!

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