ONE PERSON’S EXPERIENCE WITH PROVENGE

Malecare has an on-line support group for men with advanced prostate cancer; their loved ones and caretakers. Today, there was a post on the support group where one of the participants shared their recent experience with Provenge, including some very specific recommendations for anyone else thinking of having the treatment. You can join us by [...]

Zoledronic Acid Shows Improved Clinical Outcomes When Administered Prior to Bone Pain in Men with Advanced Prostate Cancer

According to the FDA approval label, zoledronic acid (Zometa) should be administered to men with advanced prostate cancer once they have failed one hormone therapy type, in other words, once the cancer has become castrate resistant. Researchers at the Centre Hospitalier de i’Université de Montréal, Hôpital Notre-Dame, Montréal, Quebec, Canada evaluated the effect of zoledronic [...]

Denosumab delays the Spread of Prostate Cancer to the Bones, But it Doesn’t Extend Life!

Results from a recent clinical trial indicate that denosumab delayed the spread of prostate cancer metastases bones, however it did not prolong the lives of men. […]

Capesaris™ (GTx-758) Phase II Proof of Concept Trial – A New On the Horizon Drug To Watch

GTx, Inc. this weekend presented results of the Capesaris™ (GTx-758) proof of concept pharmacokinetic-pharmacodynamic (PK/PD) clinical trial treating men with advanced prostate cancer, at the Annual Meeting of the Society of Urologic Oncology. Capesaris is a novel oral selective estrogen receptor alpha agonist which GTx is developing for first line treatment of advanced prostate cancer. [...]

Prostate Cancer Treatment Linked to An Increased Risk of Developing Colon Cancer

What is the primary treatment for men with advanced prostate cancer? We all know the answer, it is hormone therapy. Almost without exception, when we get diagnosed, we are put on to hormone therapy (ADT). ADT makes us feel terribly, it affects our stamina, our memory, our attention span, gives us hot flashes and weakens [...]

Malecare’s Advanced Prostate Cancer Program

Malecare is pleased to announce several new enhancements to our Advanced Prostate Cancer Program as well as the release of our new Advanced Prostate Cancer Kit which includes our newest publication: RECURRENT PROSTATE CANCER A Working Document for Men with Recurrent Prostate Cancer For many years, Malecare has been the leader in the fight against [...]

A Survival Advantage – Is It Worth It and What Does It Mean? When Economics Interface with Survival

In order to get FDA approval, drugs must first go through a clinical trial that demonstrates that they offer a better treatment result than the current standard of care. In some instances the better result can be a demonstration that the investigational drug provides an advantage which is only palliative (as Mitoxantrone does for advance [...]

Out On the Limb – Predicting the CME Decision on Provenge

Today, I spent most of the day listening to the CME (Medicare & Medicaid) hearing on Provenge. CME does not have to abide to the decisions of the advisory committee, so like we experienced with the FDA Advisory Committees we will have to wait and see what will eventually become the policy for reimbursement. I [...]

BMI & Prostate Cancer Recurrence

There has been a lot of controversy over the association between obesity and the eventual biochemical failure of men treated for prostate cancer. Research performed at the Cleveland Clinic, Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio attempted to determined whether there is an association between body mass index and biochemical failure [...]

Prognostic Markers for Survival for Men Who Receive Radiation Post Surgery

Men who experience a reoccurrence post surgery will usually be referred for salvage radiation therapy. The goal of the radiation is to simply eliminate the stray cancer cells that might have remained in the prostate bed. The only way we currently have to monitor the outcomes from this radiation is to monitor PSA. Researchers at [...]

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