Understanding APC

Morbidity and Treatment Regret in Men with Recurrent Prostate Cancer

Researchers wanted to determine if concurrent the development of morbidity issues ( i.e.- myocardial infarction, congestive heart failure, angina, diabetes, stroke, circulation problems, inflammatory bowel disease, or amputation) is associated with treatment regret among men with PSA recurrence following failed primary therapy for prostate cancer. The researchers evaluated 795 men from the Comprehensive, Observational, Multicenter, [...]

By Malecare|2017-10-19T10:53:17-04:00February 24th, 2011|Advanced Prostate Cancer, Drugs & Treatments, General Information, Prostate Ponderings, Research, Uncategorized, Understanding APC|0 Comments

A phase III Trial Comparing Intermittent versus Continuous ADT for Men with PSA Progression after Radiotherapy

In prior studies with men who have had a PSA recurrence after radiotherapy (RT), intermittent androgen suppression (IAS) has been suggested to improve quality of life (QoL) but effects on survival are unknown. The researchers performed an inter-group randomized phase III trial, which compared IAS vs continuous androgen deprivation (CAD) to test overall survival (OS) [...]

By Malecare|2011-02-22T11:11:47-05:00February 22nd, 2011|Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, Hormone Therapy, Radiotherapy, Uncategorized, Understanding APC|0 Comments

Caution- Do Not Combine Chemotherapy for Prostate Cancer with Avestin

An article appearing today the Urology Times E-News rang a warning bell about the use of the angiogenesis inhibitor bevacizumab (Avastin). The article warned that men with advanced prostate cancer may be at an increased risk of treatment-related death when bevacizumab is used in combination with other therapies. Senior author Shenhong Wu, MD, PhD, and [...]

By Malecare|2011-02-18T11:57:00-05:00February 18th, 2011|Advanced Prostate Cancer, Cabazitaxel, Chemo Therapy, Chemo Therapy Failure, Drugs & Treatments, General Information, Research, Uncategorized, Understanding APC|0 Comments

The effect of PSA doubling time (PSADT) and Gleason score on the PSA at the time of initial metastasis in men with biochemical recurrence after prostatectomy.

The researchers took a cohort of 430 men with a biochemical recurrence (PSA increase only) after failed prostatectomy. The men underwent observation until they experienced metastatic disease as determined by CT or bone scan. The researchers then evaluated the PSA at the time the men developed metastasis for those patients who developed metastatic disease. PSA [...]

By Malecare|2017-10-19T10:53:17-04:00February 17th, 2011|Advanced Prostate Cancer, General Information, Metastases, Research, Uncategorized, Understanding APC|2 Comments

Pomegranate Effects PSADT in Men with Advanced Prostate Cancer

Prostate cancer diets and the use of supplements have continued to be an issue faced by men fighting advanced prostate cancer. Different products seem to fall in and out of vogue; unfortunately we usually have little actual hard data on the real value of any of these products. The use of pomegranate with the goal [...]

By Malecare|2020-02-04T10:13:14-05:00February 16th, 2011|Advanced Prostate Cancer, Diet and Supplements, Drugs & Treatments, FDA, General Information, Me, Research, Uncategorized, Understanding APC|7 Comments

Surviving Chemotherapy by Stopping Unnecessary Infections

We have been having a lot of conversations on the advanced prostate cancer on-line group this last month about chemotherapy. Three of our advanced prostate cancer warriors have been openly sharing their experiences as they start docetaxel (taxotere or chemotherapy). Join the group at: Join the advanced prostate cancer on-line support group. It is important [...]

By Malecare|2020-02-04T08:09:35-05:00February 15th, 2011|Advanced Prostate Cancer, Chemo Therapy, Drugs & Treatments, General Information, How We Live, Uncategorized, Understanding APC|0 Comments

IxMP – A Potential Second or Third Line Chemotherapy- On The Horizon

Can IxMP Be Used as a Second or Third-Line Chemotherapy for Metastatic Castrate Resistant Prostate Cancer? There was a report recently released about a Phase 2 study from the Department of Defense funded Prostate Cancer Clinical Trials Consortium that suggests that ixabepilone + mitoxantrone + prednisone may have clinically significant activity as a form of [...]

By Malecare|2017-10-19T10:53:18-04:00February 14th, 2011|Advanced Prostate Cancer, Chemo Therapy, Chemo Therapy Failure, Clinical Trials, Clinical Trials, DOD, Drugs & Treatments, On The Horizon, Uncategorized, Understanding APC|0 Comments

Disease Risk, Not Age, Should Influence Prostate Cancer Treatment Decisions

Should treatments offered to older men with high risk prostate cancer be different than for younger men? Researchers from the University of California, San Francisco found that older men were denied more aggressive treatments because of their age. Men older than 75 years of age with high-risk prostate cancer often are under-treated when compared to [...]

By Malecare|2017-10-19T10:53:18-04:00February 11th, 2011|Advanced Prostate Cancer, Drugs & Treatments, General Information, How We Live, Politics of Cancer, Uncategorized, Understanding APC|0 Comments

One Large Step for Prostate Cancer and One Very Small Step for Men – Whole Genome Sequencing for Prostate Cancer

Yesterday the Prostate Cancer Foundation (PCRF) made a major announcement, it has sequenced the of whole cancer genomes of seven different men with aggressive prostate cancer. This is a historic development in the fight against prostate cancer, however, it is a small step for those of us on the ground. The eventual goal of projects [...]

By Malecare|2020-02-04T08:52:45-05:00February 10th, 2011|Advanced Prostate Cancer, General Information, genetics, Genomics, On The Horizon, Research, Uncategorized, Understanding APC|0 Comments

One Man’s Experience Fighting The Side Effects of Jevtana (Cabaziltaxel)

A member of the advanced prostate cancer on-line group recently posted about his experience using the newly approved chemotherapy agent, Jevtana (cabazitaxel). His post included not only a report about his PSA response to the drug, but his experiences with side effects and a suggested method of controlling one of the debilitating side effect, diarrhea. [...]

By Malecare|2020-02-04T08:09:23-05:00February 9th, 2011|Advanced Prostate Cancer, Cabazitaxel, Chemo Therapy, Drugs & Treatments, General Information, Personal Experiences, Uncategorized, Understanding APC|0 Comments