The Potental Use of Dutasteride in the Treatment of Hormone Refractory Prostate Cancer

Common practice is to treat men with advanced prostate cancer with androgen inhibition therapy (ADT) with or without antiandrogens (Casodex). Most of our prostate cancer will progress and develop into androgen-independent prostate cancer despite our achieving castrate testosterone levels. Dutasteride, a 5-alfa-reductase inhibitor, is commonly used in the treatment of benign prostatic hyperplasia (BPH). Additional, [...]

Danger BRCA1 & BRCA2 Genes and Prostate Cancer

A faulty gene closely associated with breast cancer is also responsible for a particularly dangerous form of prostate cancer, research has confirmed. The British Journal of Cancer reported a study that a University of Toronto research team found prostate cancer patients carrying the BRCA2 gene lived on average for four years after diagnosis as opposed [...]

Radiation Therapy Improves Survival Benefits for Men with Recurrent Prostate Cancer – A New Study

When I returned from the conference (see yesterday’s post) I kept seeing notices and announcements from a new retrospective study out of John;s Hopkins that showed that men with prostate cancer tumors that recur after prostate cancer surgery are three times more likely to survive their disease long term if they undergo radiotherapy within two [...]

Bone Metastases

Prostate cancer preferentially metastasizes to bone and the mortality from prostate cancer is 70% once bone metastases are present. In addition, prostate cancer-induced bone metastases are associated with significant complications including severe pain, skeletal fractures, spinal cord compression and bone marrow suppression. Most doctors structure their treatment protocols against bone metastases by treating the cancer [...]

PSA Levels & PSA Velocity (Doubling Time) Is Predictive of Your Survival Time

According to a recent presentation by Mitchell C. Benson, MD*, at the 32nd Winter Urologic Forum - State-of-the-Art in Urology - January 25-29, 2008 - Vail, Colorado, USA most men who have failed a local, primary therapy and then experience a rising PSA will find that their follow-up therapy will most probably consist of anti-androgen [...]

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