Intermittent ADT, Does It Increase A Man’s Risk Factors For Serious Side Effects?

Once again we see what seems to be logical isn’t necessarily the way it actually works!  In a surprising study result, it was shown that the use of intermittent androgen-deprivation therapy (IADT) for prostate cancer is not associated with fewer long-term adverse events than continuous ADT!  Who would have guessed? We all thought that intermittent [...]

CTC Heterogeneity Predicts Prostate Cancer Drug Sensitivity

This afternoon I am off to the American Society for Clinical Oncology Genitourinary Cancers Symposium (ASCO GU) in San Francisco. There has already been some information leaking to the media about some of the presentations that will be going on at the conference. One such “leak” is about  findings from Memorial Sloan Kettering Cancer Center [...]

What Are The Negative Prognostic Factors You Should Know When You Have A Biochemical Prostate Cancer Occurrence

Knowing the negative prognostic factors for successful treatment when you have a   a biochemical recurrence (PSA only) of your prostate cancer is important. These factors can help you make your treatment decisions because they assist you in evaluating your possible clinical outcome. In a single institutional review of  negative prognostic outcomes of salvage radiotherapy in [...]

Understanding the Result of Neuroendocrine Differentiation in Prostate Cancer

Understanding a little about the prostate gland and its biology is not only interesting, but it allows us to ask some important questions that can be very specific to our prostate cancer treatment decisions and our eventual outcomes from these decisions. It also can simply add to the confusion we all face in making the [...]

Using Low Dose Prednisone in First-Line Docetaxel Treatment Improves The Quality of Life (QoL) For Men With Prostate Cancer

Clinical trials are used to both demonstrate that a drug or treatment has efficacy (extends life or improves the quality of life). They also are used as the vehicle to obtain approval from the governmental body responsible for monitoring and approving their use. How the trial is set up will directly dictate the eventual approved [...]

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