FDA Approves New Indications for Prolia® (Denosumab) for the Treatment of Bone Loss in Men with Prostate Cancer Undergoing ADT

Amgen announced that the U.S. Food and Drug Administration (FDA) has approved two new indications for Prolia® (denosumab) as a treatment to increase bone mass in men receiving androgen deprivation therapy (ADT) for non-metastatic prostate cancer. Men receiving ADT are at high risk for developing fractures, including vertebral fractures, which can cause paralysis. "Bone loss [...]

Genetics & Calcium Might Increase Risk for Prostate Cancer In the African-American Men

A study by at Wake Forest Baptist Medical Center in Winston-Salem N.C., Keck School of Medicine at the University of Southern California (USC) and the Cancer Prevention Institute of California suggests that a high intake of calcium causes prostate cancer among African-American men who are genetically good absorbers of the mineral. According to Gary G. [...]

Should Bisphosphonates Use Be Limited- An FDA Panel Waffles on Limiting Duration

A recent meeting of an FDA advisory committee has asked wants the FDA to limit the duration of bisphosphonate therapy for treatment of osteoporosis, but the committee could not agree on a time limit to recommend. […]

The Impact of Hypertriglyceridemia On Prostate Cancer Development in Men Over 60 Years

An interesting, but it makes sense type of study, was discussed about the relationship between high levels of triglycerides (TG) and the development of prostate cancer, including more aggresive prostate cancer. It of course follows suite that prostate cancer diagnosed with higher gleason scores (more aggressive) leads to more advanced prostate cancer. This study which [...]

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