Science and good medicine is not always what it seems. We all believe that if something is logical it must be true, but often the most logical assumptions we make do not stand up to good scientific inquiry. Many of us choke on the fact that Provenge extends life while it has no effect on [...]
In a study conducted by Choueiri et al. published in Cancer it was suggested that men who have prostate cancer that was treated by a radical prostatectomy (RP) who then had a long time to a biochemical recurrence (BCR) or a long PSA doubling time after a BCR have no higher overall risk of death [...]
According to an article published in URO Today the belief that adjuvant androgen suppression therapy (AST) is associated with early deaths due to myocardial infarctions (MCIs) is not true. The belief that ASTs increases deaths from MCIs comes from the TROG 96.01 trial conclusions. Now there has been a retrospective, long term (ten year) meta-analysis [...]
My very dear friend and advocate supreme, Jan Manarite, from PCRI has sent me an update on MDV3100 (enzalutamide). As usual her information is important, so I thought I would pass it on today. • She points out that once the FDA approves MDV3100 (I am going to work on the assumption that it will [...]
Finally, we are getting a little common sense discussion about the role of PSA screening. Not to beat a dead horse, but as we all know the United Sates Preventive Task Force (USPTF) changed their rating of the PSA test from a D to a F. The result of this change is that many doctors, [...]