The Development of A Novel Blood Biomarker for Detecting AR-V7 and Resistance to Zytiga and Xtandi

At the current AUA Annual Meeting going on in New Orleans, there was a presentation given by Haitao Zhang and colleagues. They described their work developing a novel blood-based assay (test) for detecting androgen receptor (AR) splice variants in men with advanced prostate cancer. Their work relies on the premise that AR-V7 expression underlies resistance [...]

Predicting the Long-Term Survival of Men with A Biochemical Recurrence Post-Surgery Who Are Hormone Naive Can Change How We Treat Them

Appearing in the European Journal of Nuclear Medicine and Molecular Imaging a recent study provides data on the long-term survival of men with a biochemical recurrence after failed surgery. In the study by Giovacchini et al. it was shown that a PET/CT scan (specifically a [11C] choline PET/CT) could predict the long-term survival of men [...]

Evidence Based Data Showing importance of Survivorship Care For Cancer Survivors

Survivorship and survivorship care increasingly takes on a more important role in the care of cancer patients. Over time we will continue to see an ever increasingly emphasize on survivorship as our medical interventions improve, expanding the number of cancer survivors. Today, cancer survivors are becoming a force, demanding increasing research dollars (although not as [...]

More People Surviving Cancer, But There Remains Groups That Have Not Had A Benefit

The good news is that many more people are surviving years after a cancer diagnosis. According to a new analysis the proportion of people surviving cancer is increasing through out the United States. The analysis showed that for both men and women aged 50 to 64 who were diagnosed between 2005 to 2009 with a [...]

Understanding How Personalized Medicine Is Developed By Way Of A Real Situation – Olaparib

It is common knowledge that men with metastatic castration-resistant prostate cancer (CRPC) don’t all have the same disease. There are many different types or flavors of prostate cancer. These differences are involved in the genetic structure of the cancer cell its self. Some prostate cancers have mutations in the DNA repair genes (genes whose job [...]

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