Outcomes of Locally Advanced (T3 or greater) Prostate Cancer in Men Undergoing Robot-Assisted Laparoscopic Prostatectomy

Stories abound about men who undergo prostate cancer surgery only to have the surgery halted when their doctor sees that the cancer has left the gland. The stories go that the doctor stops the surgery leaving the gland and any other visible tumors in place just as they found them. Current statistics indicate that one [...]

Confirming Hormone Therapy Increases The Risk for Heart Diseases

Confirming a belief of many of us, new research has found that hormone therapy (endocrine therapy or ADT) is associated with a very large increased risk of developing various major heart problems. This research also tells us that some therapy options have a higher risk profile than others. At Europe's biggest cancer congress, ECCO 15 [...]

Younger Men With Advanced Prostate Cancer Have A Shorter Lifespan

Advanced prostate cancer poses a deadly paradox for younger men (aged 35 to 44 years). Younger men diagnosed with advanced prostate cancer will have a shorter remaining life span than older men who develop the disease, despite the fact that in general younger men have a much lower risk of dying from prostate cancer. Daniel [...]

Cancer Survivors and Stress

I have often hypothesized that stress can escalate the rate of prostate cancer progression, leading to earlier deaths. I work actively to find ways to eliminate stress from my immediate environment and from my life. I have told the story many times about two men who were members of my weekly Malecare prostate cancer support [...]

PET/CT Scans May Help Detect Recurring Prostate Cancer Earlier

The September issue of The Journal of Nuclear Medicine published a study that shows that positron emission tomography (PET)/computer tomography (CT) scans using the imaging agent choline could detect recurring prostate cancer sooner than conventional imaging technologies in some men who have had prostatectomy. Men who elect to have a radical prostatectomy to treat prostate [...]

Patient Care Costs in Clinical Trials – A Problem

Clinical trials are the lifeblood of new drug and treatment development. Trials allow us to learn what developing drugs and treatment are both safe and effective. Many drug developers complain about their inability to attract enough volunteers to reach a sample size that will allow them to draw statistically valid conclusions. Everyday there are trials [...]

PET/CT Scans May Help Detect Recurring Prostate Cancer Earlier

The September issue of The Journal of Nuclear Medicine published a study that shows that positron emission tomography (PET)/computer tomography (CT) scans using the imaging agent choline could detect recurring prostate cancer sooner than conventional imaging technologies in some patients who have had their prostates surgically removed. Men who elect to have a radical prostatectomy [...]

C-Reactive Protein as Adverse Prognostic Marker for Men with Castration-Resistant Prostate Cancer

A confirmatory study evaluating the prognostic value of C-reactive protein (CRP) levels in men with castrate-resistant prostate cancer (CRPC) was presented at the 2009 American Society of Clinical Oncology (ASCO) conference in Orlando Florida. Historically, CRP has been associated with adverse outcomes in men with CRPC treated with docetaxel. This study, presented by R. Prins, [...]

Factors Pointing to the Development of Metastatic Prostate Cancer

It is inevitable; most men with prostate cancer, who require treatment with androgen deprivation therapy (ADT), will eventually become resistance to treatment leading to the development of metastatic disease. Men who develop metastatic castrate-resistant disease have a very poor prognosis. Historically, their overall survival is estimated only to be 24 to 36 months. A study [...]

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