Drugs & Treatments

FDA Approves New Indications for Prolia® (Denosumab) for the Treatment of Bone Loss in Men with Prostate Cancer Undergoing ADT

Amgen announced that the U.S. Food and Drug Administration (FDA) has approved two new indications for Prolia® (denosumab) as a treatment to increase bone mass in men receiving androgen deprivation therapy (ADT) for non-metastatic prostate cancer. Men receiving ADT are at high risk for developing fractures, including vertebral fractures, which can cause paralysis. "Bone loss [...]

By |2011-09-19T10:59:59-04:00September 19th, 2011|Advanced Prostate Cancer, Bone Mineral Density, Drugs & Treatments, FDA, General Information, Hormone Therapy, Prolia (denosumab), Uncategorized, Understanding APC|3 Comments
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Should Bisphosphonates Use Be Limited- An FDA Panel Waffles on Limiting Duration

A recent meeting of an FDA advisory committee has asked wants the FDA to limit the duration of bisphosphonate therapy for treatment of osteoporosis, but the committee could not agree on a time limit to recommend. […]

By |2011-09-13T10:46:54-04:00September 13th, 2011|Advanced Prostate Cancer, bisphosphonates, Bone Mineral Density, Drugs & Treatments, FDA, Uncategorized, Understanding APC, Zometa|0 Comments
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New Data on Long-Term Use of Firmagon® (degarelix) For Men with Advanced Hormone Dependant Prostate Cancer

New data, published September 1 in the Journal of Urology, shows that Firmagon® (degarelix) which is a gonadotropin-releasing hormone therapy (GnRH) given to men with advanced prostate cancer may be superior to leuprolide when used over three years. This new study (CS21A) was an open-label extension of the Phase III study (CS21) in which Firmagon® [...]

By |2011-09-04T12:51:17-04:00September 4th, 2011|Advanced Prostate Cancer, Drugs & Treatments, Firmagon (degarelix), Uncategorized, Understanding APC|0 Comments
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Cabozantinib, Promising, Still Controversial For the Treatment of Bone Mets in Prostate Cancer

Cabozantinib (cabo), has many of us prostate cancer survivor, educators and researchers simply scratching their heads. In trials, Cabozantinib demonstrated what some people have characterized as mind boggling activity against bone metastases. In trials the drug led to partial or complete resolution of bone scans in a substantial portion of patients with cancer, including prostate, [...]

By |2017-10-19T10:52:06-04:00August 24th, 2011|Advanced Prostate Cancer, Alpharadin (radium-223), cabozantinib, Drugs & Treatments, General Information, Imaging, Metastases, Research, Uncategorized, Understanding APC|3 Comments
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Identifying A New Pathway Explaining Resistance to Prostate Cancer Treatment

We al are very familiar with the significant problem in the treatment of prostate cancer, even therapies that initially work stop working and our disease continues to progress. The inevitable onset of this resistance to treatment with antiandrogens (ADT) such as Lupron or Zoladex is not limited just to this class of drugs. We have [...]

By |2017-10-19T10:52:07-04:00August 18th, 2011|abiraterone acetate, Advanced Prostate Cancer, Chemo Therapy Failure, Drugs & Treatments, General Information, Hormone Therapy, Research, Uncategorized, Understanding APC|10 Comments
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Decreased Prostate Cancer-Specific Survival of Men with BRCA2 Mutations and for Men from Breast Cancer Families

It is fairly common practice for those diagnosed with breast cancer to have genetic testing. Genetic testing is almost unheard of when men are diagnosed with prostate cancer. Current research shows that genetic testing for men with prostate cancer could provide important information about both potential treatment efficacy and prognosis. A recent look at the [...]

By |2017-10-19T10:52:09-04:00August 17th, 2011|Advanced Prostate Cancer, Drugs & Treatments, General Information, genetics, Genomics, Research, Uncategorized, Understanding APC|0 Comments
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A Provenge Like Treatment Demonstrates Extraordinary Results Treating Leukemia – A Phase I Trial Using the Technique In Post Chemo Prostate Cancer Treatment

The most exciting news today is about some research performed at the University of Pennsylvania where researchers took blood from the three leukemia patients and isolated the T cells, a type of immune cell in the blood. T cells recognize invading organisms and kill them, however they do not recognize cancer cells as invading cells, [...]

By |2020-02-04T11:34:16-05:00August 12th, 2011|Advanced Prostate Cancer, Chemo Therapy Failure, Clinical Trials, Clinical Trials, Drugs & Treatments, On The Horizon, Uncategorized, Understanding APC, vaccines|2 Comments
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Towards An Understanding of the Role of Genetics in Determining Future Treatment Options in Advanced Prostate Cancer – SLCO2B1 and SLCO1B3

We have heard for a period of time that the future of cancer treatment is in genetics. Despite the hubbub, we see very little hard evidence of this in today’s current treatment decisions. Treatment still remains tied into protocols with a strong bias to following a common map. Each map does have little variances, but [...]

By |2017-10-19T10:52:10-04:00August 11th, 2011|Advanced Prostate Cancer, Drugs & Treatments, genetics, Genomics, Hormone Therapy, Uncategorized, Understanding APC|0 Comments
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Prostate Cancer Survivors Should be Prescribed Exercise

According to a report released recently by the UK charity Macmillan Cancer Support exercise can benefit cancer survivors, including prostate cancer survivors. This report disproves the theory that those suffering with cancer or who have beaten the disease should simply rest. Rest no more, exercise should be prescribed to those at all stages of cancer [...]

By |2017-10-19T10:52:10-04:00August 10th, 2011|Advanced Prostate Cancer, Drugs & Treatments, General Information, How We Live, Research, Uncategorized, Understanding APC|0 Comments
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