Drugs & Treatments

Degarelix Proves to be the Superior Hormone Deprivation Treatment (ADT) for Men with Advanced Prostate Cancer

Based on six recent retrospective analyses comparing the gonadotropin-releasing hormone (GnRH) antagonist degarelix against the traditional luteinizing hormone-releasing hormone (LHRH) agonists (i.e. Zoladex, Lupron etc.) men with advanced prostate cancer experienced improved disease control, fewer instances of urinary infections, and a lower risk of cardiovascular events. The six analyses compared data from randomized trials that [...]

By Malecare|2017-10-19T10:49:17-04:00November 5th, 2013|Advanced Prostate Cancer, Drugs & Treatments, Firmagon (degarelix), Hormone Therapy, Research, Uncategorized, Understanding APC|2 Comments

Bone Disease in Men with Prostate Cancer Needs Constant Monitoring

The number of cancer survivors is increasing, soon to be as many of 13 million of us in the world! Bones are often affected in cancer survivors, usually a result of bone metastases, or of anti-cancer therapies which can contribute to bone loss and fragility. Bone disease in cancer survivors can result both from the [...]

By Malecare|2013-11-04T20:25:00-05:00November 4th, 2013|Advanced Prostate Cancer, bisphosphonates, Bone Metastases, Bone Mineral Density, denosumab - Xgeva, Drugs & Treatments, General Information, Hormone Therapy, Quality of Life, Uncategorized, Understanding APC, Zometa|0 Comments

Why Xofigo is Superior to Other Radiopharmaceuticals for Advanced Prostate Cancer Treatment

We are in the fortunate position because the treatment of men with metastatic castration-resistant prostate cancer (mCRPC) continues to evolve as new agents with the ability to extend survival gain FDA approval. The most recently FDA approved treatment, the alpha emitting radiopharmaceutical radium-223 (Xofigo) was approved for men with bone metastatic prostate cancer. Most other [...]

By Malecare|2013-10-31T13:13:04-04:00October 31st, 2013|Advanced Prostate Cancer, Alpha Emitting Radio Therapy, Alpharadin (radium-223), Bone Metastases, Clinical Trials, Clinical Trials, Drugs & Treatments, radiopharmaceuticals, Uncategorized, Understanding APC, Xofigo|8 Comments

Is Zytiga with Prednisone Effective in Men with Metastatic Prostate Cancer Who Have Visceral Disease?

Castate resistant metastatic prostate cancer (mRPC) withvisceral disease (tumors involving the internal organs of the body, specifically those within the chest (as the heart or lungs) or abdomen (as the liver, pancreas or intestines) is a negative prognostic factor. In many cases clinical trials of new investigational drugs rule out men with visceral disease from [...]

By Malecare|2017-10-19T10:49:21-04:00October 29th, 2013|abiraterone acetate, Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, Quality of Life, Research, Uncategorized, Understanding APC, Zytiga|0 Comments

To Stay Alive Avoid the Hospital on Weekends and Night Time If Possible

In prior posts I have strongly recommended that, if possible, it is in your best interest not to go into the hospital in the month of July. The month of July is the traditional beginning of a new rotation for the new hospital Residents, or there are an overwhelming number of newly minted doctors with [...]

By Malecare|2020-02-04T11:50:38-05:00October 25th, 2013|Advanced Prostate Cancer, Drugs & Treatments, General Information, How We Live, Politics of Cancer, Uncategorized|0 Comments

Positive Results for Xtandi in the Pre-Chemotherapy Space

It was announced today that after observing significant benefits in overall survival (OS) and radiographic progression free survival (PFS) ,the two co-primary endpoints of the the Xtandi pre-chemotherapy trial, the Independent Data Monitoring Committee (IDMC) for The Phase 3 PREVAIL trial of enzalutamide in metastatic prostate cancer recommends that "the study be stopped and patients [...]

By Malecare|2017-10-19T10:49:22-04:00October 22nd, 2013|Advanced Prostate Cancer, Drugs & Treatments, Early/Expanded Access Programs, enzalutamide, Enzalutamide (MDV-3100), Fail First Therapy, General Information, Provenge, step therapy, Uncategorized, Understanding APC, Xtandi, Zytiga|1 Comment

Step Therapy – The Creeping Crud Infecting Our Care Takes Another Bite Out Of Our Treatment

Step therapy (ST) has again reared its most ugly head in our prostate cancer world, to the detriment of us, prostate cancer survivors and only to the benefit of private insurance payers. So, what is this “creeping crud,” Step Therapy (aka as Fail First Therapy)? Simply, ST is when insurance companies decide, without sound medical [...]

By Malecare|2020-02-04T08:41:02-05:00October 18th, 2013|abiraterone acetate, Advanced Prostate Cancer, Drugs & Treatments, Enzalutamide (MDV-3100), FDA, General Information, step therapy, Uncategorized, Xtandi, Zytiga|0 Comments

WHAT – Fired By Your Doctor! Sounds Like You Are Lucky

I want to share a post I made today on the advanced prostate cancer online support group ). It was in response to an ongoing thread with a spouse (caregiver) who was fired by her husband's doctor by having his nurse call them. She was guilty of asking questions, relevant and important ones, but the [...]

By Malecare|2021-02-17T11:03:09-05:00October 17th, 2013|Advanced Prostate Cancer, Drugs & Treatments, General Information, How We Live, Our Caretakers, Uncategorized, Understanding APC|2 Comments

Is Zytiga Working and When to Move on to Another Treatment? Knowing by Counting Your CTCs

At the 2013 European Cancer Congress in Amsterdam Dr. Howard Scher from Sloan Kettering Hospital reported that a panel of biomarkers could identify men with metastatic, castration-resistant prostate cancer (mCRPC) who were responding well or less well to treatment with Zytiga + prednisone (abiraterone + prednisone). Dr. Scher provided data in his presentation to support [...]

By Malecare|2013-10-10T16:00:13-04:00October 10th, 2013|abiraterone acetate, Advanced Prostate Cancer, Clinical Trials, Clinical Trials, CTCs, Drugs & Treatments, General Information, Uncategorized, Understanding APC, Zytiga|0 Comments

Oligometastatic Prostate Cancer – Still Curable So Be Vigilant

It is generally agreed that prostate cancer which is still 100% confined to the prostate gland is curable using local therapies like radiation or surgery, but when it has left the prostate gland and becomes metastatic it is no longer curable. Treatment for metastatic prostate cancer is intended to make the prostate cancer a chronic [...]

By Malecare|2017-10-19T10:49:23-04:00October 9th, 2013|Advanced Prostate Cancer, Bio Chemical Recurrence, Bone Metastases, Drugs & Treatments, General Information, Hormone Therapy, oligometastic, Uncategorized, Understanding APC|7 Comments