Tasquinimod (TASQ)- A New Phase 3 Trial Shows Promise To Slow Disease Progression

Results from a recent international randomized phase II trial for the drug tasquinimod (TASQ), shows that TASQ is a potential therapy for men with advanced prostate cancer. The men who received TASQ on average went twice as long without disease progression as those who received only a placebo. […]

Pomegranate and Its Role In PSA Velocity

In 2005 there was a small clinical trial performed at UCLA evaluating pomegranate juice and its ability to control PSA for men with prostate cancer. The trial gave 8 oz. of POM Wonderful pomegranate juice each day in men with a rising PSA post treatment (recurrent advanced prostate cancer). This trial, which was funded by [...]

Status Update on the Budget and It’s Implications for Cancer Research

As of now, Congress and the Administration are at an impasse on FY 11 spending.  If no deal is reached by Friday, government operations will shut down.  This would impact cancer research and prevention programs in the following ways: *   Patient enrollment in clinical trials would be discontinued; *   No new grants would be awarded; [...]

Carboplatin – A 2nd line chemotherapy?

Carboplatin is a chemotherapy agent used for treatment of many types of cancer. Currently, it is approved by the Food & Drug Administration (FDA) for treating patients with ovarian and non-small cell lung cancer. However, some oncologists use carboplatin “off-label” for other cancers. Commonly, these “off-label” uses include testicular, stomach, and bladder cancers as well [...]

New Phase 2 Trials For MDV3100 Begins & Another To Start Soon – On The Horizon

It was announced today that the first patient in the TERRAIN study received their first dose in the Phase 2 trial of the investigational drug MDV3100 . MDV3100 is a triple-acting oral androgen receptor antagonist that I have writing about as a drug “On The Horizon”. Triple-acting means that it blocks testosterone binding to the [...]

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