I suffered with significant hot flashes when I was on androgen deprivation therapy (ADT). I experienced between seven to 15 flashes in a twenty-four hour period. Often the flashes were accompanied with breathing difficulties and fatigue. My quality of life was significantly negatively affected. The flashes were significant enough to require that I occasionally change [...]
What do advanced prostate cancer survivors do once we fail chemotherapy? At this time there are no FDA approved next steps other than to take some time off and pray that restarting chemotherapy will again help us. To put in another way, we wait to die. There is a huge need to find additional strategies [...]
At the University of New Mexico School of Medicine in Albuquerque, New Mexico (SKS) the Department of Urology just completed a study that showed that dutasteride, the generic name for a dual 5alpha-reductase inhibitor made by GlaxoSmithKline and marketed under the name Avodart™ in the US and Avolve™ in Europe, when administered to men with [...]
There is a lot of pressure on cancer survivors to participate in clinical trials. Without the brave individuals willing to participate in the trials research would grind to a halt along with new, improved treatments for all cancers. Even though an estimated 2.3 million people in the United States take part in clinical trials every [...]
Did you have androgen deprivation therapy (ADT)? If you have you probably experienced hot flashes. Up to 80% of men treated with ADT for prostate cancer will experience hot flashes, ranging from very mild to very severe. Along with hot flashes many of us will also have insomnia, fatigue, irritability and a host of other [...]
A study which was funded by Cell Pathways Inc., developer of the drug Exisulind, suggest that Exisulind may delay disease progression in men with recurrent prostate cancer according to Dr. Erik Goluboff, Assistant Professor of Urology at Columbia University College of Physicians & Surgeons, Director of Urology at The Allen Pavilion of New York-Presbyterian Hospital, [...]
At the last ASCO Annual Meeting Saad et al. presented a report about a Phase II trial of custirsen (OGX-011) + docetaxel + prednisone vs. custirsen + mitoxantrone + prednisone in metastatic hormone-refractory prostate cancer. The subjects in the study had experienced relapses of cancer progression within 6 months of treatment with first-line docetaxel therapy. [...]
I have to admit that cancer researchers are becoming very creative. There is a phase II clinical trial getting ready to start at the Wake Forest University Baptist Medical Center which has a new twist. The treatment is based on injecting white blood cells called 'cancer killing' granulocytes from healthy donors into cancer survivors with [...]
Hollis-Eden Pharmaceuticals, Inc. (NASDAQ:HEPH) has announced a new phase I/II clinical trial of Apoptone (HE3235) for late stage prostate cancer. Howard Scher, M.D., Chief of the Genitourinary Oncology Service at Memorial Sloan-Kettering Cancer Center said "The preclinical data generated to date suggest that Apoptone may offer a unique therapeutic approach to late-stage prostate cancer where [...]
Posted on the Prostate Problems Mailing list about two months ago was a notice from Dr. Richard Lam about a clinical trial in which his office, Prostate Oncology Specialists, will participate. What I found particularly interesting in this trial is that it was evaluating a potential new drug, abiraterone acetate, which could be used after [...]
