Apalutamide Looking Good as Treatment for Non-Metastatic Castrate Resistant Prostate Cancer

Non-Metastatic Castrate Resistant Prostate Cancer (nmCRPC)  usually leads to metastatic prostate cancer and death. There are no approved treatments for nmCRPC. Apalutamide is a taken-by-mouth androgen receptor inhibitor with antitumor activity in CRPC. There's a much talked and written about clinical trial called, SPARTAN, that investigated how well Apalutamide works on maintaining metastasis-free survival (MFS) [...]

XTANDI (enzalutamide) plus androgen deprivation therapy (ADT) reduces developing metastases or death

Non-metastatic Castrate Resistant prostate cancer patients take note.  The Phase 3 PROSPER trial in patients with non-metastatic (M0) Castration-Resistant Prostate Cancer (CRPC) showed that the use of XTANDI® (enzalutamide) plus androgen deprivation therapy (ADT) significantly reduced the risk of developing metastases or death by 71 percent compared to ADT alone.  It will be a [...]

Metastatic Prostate Cancer – Bone Metastases Might Be Controled With Xofigo For Two or More Years

Metastatic Prostate Cancer suffers have good news.  Xofigo, also known as Radium-223 (Ra-223), is a treatment for patients with castration-resistant prostate cancer (CRPC) and symptomatic (you can feel them) bone metastases (mets).  Early results of an international, open-label, phase 1/2 study (NCT01934790) showed that re-treating pts with Ra-223 was well tolerated with favorable effects on [...]

By |2018-02-06T11:09:18-05:00February 5th, 2018|Advanced Prostate Cancer, Hormone Therapy|0 Comments

Prostate Cancer And Anger

Anger hurts prostate cancer treatment.  I feel angry and I'm not going to take my pills or show up for IMRT session.   The thing about prostate cancer is that you’re not told what to do every step of the way or how to do it. Nothing is planned out for you, you just [...]

By |2018-02-01T11:18:25-05:00February 1st, 2018|Advanced Prostate Cancer|1 Comment

Prostate Cancer Estate and Healthcare Proxy Planning

Five Estate Planning Documents to Have When You’re Battling an Illness Whether you’re young, old, healthy, or ill, estate planning should be a top priority. However, if you’re faced with a prostate cancer or have received some other unfavorable medical diagnosis, it’s especially critical that your legal affairs are in order and up to [...]

By |2018-01-30T08:48:31-05:00January 30th, 2018|Advanced Prostate Cancer|0 Comments

Clinical Trial Search

Searching for clinical trials is almost as hard as participating in clinical trials.  clinical trial.gov is almost unusable.  There are several businesses that have tried to make searching for clinical trials easier.  Malecare is working with two of the very best.  One, we can't tell you about in detail, since they are still in [...]

By |2020-02-04T11:56:57-05:00January 22nd, 2018|Advanced Prostate Cancer|0 Comments

Advanced Prostate Cancer and Cholesterol

High serum levels of total and HDL cholesterol are associated with an elevated risk of advanced prostate cancer. Every 10mg/dl increase in serum total cholesterol adds a 5% increase to your odds of being diagnosed with advanced stage prostate cancer. Every 10mg/dl increase in HDL cholesterol increases your odds of having advanced stage prostate [...]

By |2018-01-10T12:59:05-05:00January 10th, 2018|Advanced Prostate Cancer|0 Comments

Apalutamide Study Prioritized For Non-Metastatic Canstrate-Resistant Prostate Cancer

Men with non-metastatic castrate-resistant prostate cancer will soon know whether or not apalutamide is helpful.  The USA based Food and Drug Administration has cut the review time from ten to six months.   We might hear the FDA's ruling as early as April, 2018. Apalutamide (ARN-509) is an  androgen receptor inhibitor and might prove to [...]

By |2018-01-08T14:36:05-05:00January 8th, 2018|Advanced Prostate Cancer|1 Comment

Exercise and Advanced Prostate Cancer

Exercise of any kind helps men at any stage of Prostate Cancer.   Unfortunately, many advanced stage prostate cancer patients don't exercise enough. Advanced Prostate Cancer patients worry about bone pain more than other men.  Androgen deprivation therapy, commonly called "hormone therapy," can cause bone problems.  Metastases to bones can cause severe pain that many [...]

By |2020-02-04T12:33:09-05:00January 5th, 2018|Advanced Prostate Cancer|0 Comments