About Malecare

Malecare is the world's leading men's cancer support and advocacy nonprofit organization.

Genome-wide Association Study Identifies a Genetic Variant Associated with Risk for More Aggressive Prostate Cancer

It is estimated that in the United States 200,000 men will be diagnosed with prostate cancer each year with approximately 20% to 30% having clinically aggressive prostate cancer. When diagnosed the standard is to consider factors such as Gleason score and tumor stage to assess a man’s prognosis, however there are no biomarkers to identify [...]

Identifying A New Pathway Explaining Resistance to Prostate Cancer Treatment

We al are very familiar with the significant problem in the treatment of prostate cancer, even therapies that initially work stop working and our disease continues to progress. The inevitable onset of this resistance to treatment with antiandrogens (ADT) such as Lupron or Zoladex is not limited just to this class of drugs. We have [...]

Decreased Prostate Cancer-Specific Survival of Men with BRCA2 Mutations and for Men from Breast Cancer Families

It is fairly common practice for those diagnosed with breast cancer to have genetic testing. Genetic testing is almost unheard of when men are diagnosed with prostate cancer. Current research shows that genetic testing for men with prostate cancer could provide important information about both potential treatment efficacy and prognosis. A recent look at the [...]

A Provenge Like Treatment Demonstrates Extraordinary Results Treating Leukemia – A Phase I Trial Using the Technique In Post Chemo Prostate Cancer Treatment

The most exciting news today is about some research performed at the University of Pennsylvania where researchers took blood from the three leukemia patients and isolated the T cells, a type of immune cell in the blood. T cells recognize invading organisms and kill them, however they do not recognize cancer cells as invading cells, [...]

Towards An Understanding of the Role of Genetics in Determining Future Treatment Options in Advanced Prostate Cancer – SLCO2B1 and SLCO1B3

We have heard for a period of time that the future of cancer treatment is in genetics. Despite the hubbub, we see very little hard evidence of this in today’s current treatment decisions. Treatment still remains tied into protocols with a strong bias to following a common map. Each map does have little variances, but [...]

Prostate Cancer Survivors Should be Prescribed Exercise

According to a report released recently by the UK charity Macmillan Cancer Support exercise can benefit cancer survivors, including prostate cancer survivors. This report disproves the theory that those suffering with cancer or who have beaten the disease should simply rest. Rest no more, exercise should be prescribed to those at all stages of cancer [...]

Clinical Trials for Prostate Cancer: Myths & Facts

Clinical trials are important both for your treatment and for the purpose of advancing our knowledge about drugs and treatments against prostate cancer. The treatment of advanced and recurrent prostate cancer has made significant steps over the last 2 years, but without the active participation of all of us our progress will be slowed, perhaps [...]

Important Agent Orange Information for Those Who Served in Thailand

The United States Veterans Administration (VA) has announced that, like those who served in Vietnam, veterans who served in Thailand maybe be entitled to VA benefits. Those who had served at one of the military bases in Thailand listed in the below URL and the locations at those bases identified, and experiencing any of the [...]

Using Zytiga Prior to Chemotherapy, Is It A Good Idea?

It is interesting that Dr. S. Meyers just produced a video on the issue of using the newly approved drug Zytiga (abiraterone acetate) prior to chemotherapy instead of post-chemotherapy. I find it interesting because like him, I have been receiving a number of questions about this same issue. […]

Intermittent Androgen Deprivation (IAD)- No Longer Considered Experimental for Treating Men with Advanced Prostate Cancer

Changing the Standard of Care for Men with Recurrent and Advanced Prostate Cancer, Men receiving androgen deprivation therapy (ADT) for the treatment of advanced or metastatic prostate cancer know all to well the terrible side effects this treatment modality can cause. These side effects can include fatigue, hot flashes, mood swings, inability to concentrate as [...]

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