Quality of Death. A new term we are introducing to the prostate cancer discussion. Will I die in pain, agony or in some semblance of peace? Do I want to be stupefied by opioids during my last days, hours and minutes? Do I want to enter a coma like state? Would I like to [...]
Here is the latest challenge to PSA test usefulness for Prostate Cancer screening in the USA. Malecare feels you should be empowered to participate in this national health policy issue. The U.S. Preventive Services Task Force released a new guideline, determining that the potential benefits and harms of prostate-specific antigen (PSA)-based screening in men [...]
Yervoy (ipilimumab) alone doesn’t help treat advanced prostate cancer patients. Yervoy activates the immune system by going after the CTLA-4 protein receptor that slows immune-system activity. But prostate cancer responds to Yervoy by increasing two other immune checkpoint molecules, PD-L1 and VISTA. And both send a don’t-eat-me signal to immune cells. That reaction is why Yerboy, by [...]
New molecules called selective androgen receptor degraders (SARDs) might be helpful in fighting advanced prostate cancer, according to an industry-sponsored study presented April 1, at the 99th annual meeting of the Endocrine Society. "If successful in the clinic, the novel highly potent SARDs discovered in this program could be used to treat many of the [...]
Fetal estrogen estetrol, also called E4, is being tested in the Netherlands as a treatment for advanced prostate cancer. "E4 for the treatment of prostate cancer would offer a new and affordable option compared to current standard and new therapies. An important advantage of E4 is expected to be the avoidance of the hypoestrogenic side [...]