There is a brief, but great YouTube video that very simply and clearly explains the current thinking about how and why prostate cancer becomes androgen independent (castrate resistant).
View the video by clicking here
Joel T Nowak, M.A., M.S.W.
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About the Author: Malecare
Malecare is the world's leading men's cancer support and advocacy nonprofit organization.
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This video is by Centocor Ortho, the J & J subsidiary which is responsible for Abiraterone cmmercialisation. At a likely 2500$/month.