Knowing When Zytiga and Xtandi Have Failed Even Though The PSA Is Not Consistent With Disease Progression?

On the advanced prostate cancer online support group there have been some questions raised about how we know when drugs like Zytiga and Xtandi have stopped working. Knowing this as soon as possible is important so that you can quickly move on to the next treatment without giving the prostate cancer time to progress and [...]

Who will respond to Zytiga (Abiraterone) and Xtandi (Enzalutamide)?

We have many new drugs that have been recently approved to treat advanced prostate cancer. Two of these drugs are abiraterone (Zytiga) and enzalutamide (Xtandi). These drugs offer new hope to men with advanced prostate cancer after the cancer has become resistant to hormone therapies (called "castration-resistant prostate cancer"). These drugs are a real breakthrough, [...]

Commonly Used FDA Approved Treatments for Metastatic Castrate Resistant Prostate Cancer (mCRPC)

The first line of treatment for advanced prostate cancer is Androgen (male hormone) Deprivation Therapy or ADT. Once the PSA progresses (climbs) while still on ADT and with testosterone levels

Canada Gets the Nod for the Use of Xtandi

Some good news for my neighbors immediately to my north. Enzalutamide (Xtandi) has received Health Canada's approval for the treatment of metastatic castration-resistand advanced prostate cancer in the post chemotherapy phase. This means that any man with castrate resistant prostate cancer, once they have received taxotere can now get Xtandi. Xtandi works by being a [...]

Evidence Against Step Therapy Being Good for Prostate Cancer Care

On August 13, 2013 I wrote an important post about the terrible practice beginning to rear its head called step therapy. Step therapy is the practice of insurance companies requiring less expensive drugs be prescribed prior to more expensive ones despite the comparative efficacy of the drugs and their different mechanisms of action. This practice [...]

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