C-Reactive Protein Confirmed As An Adverse Prognostic Marker for Men with Castration-Resistant Prostate Cancer (CRPC)

I have not had even two seconds to write about anything I saw at the AACR meeting. It will take me a few days to decompress and process my experience. In the mean time I thought I would share the following with you about inflammation and its role in survival and cancer: Researchers from the [...]

An Article In The Lancet Reported Positive Data From Phase 1-2 Trial Of MDV3100 for men with Advanced Prostate Cancer (4/15/10)

It was announced today that the phase I/II trial of MDV3100 demonstrated positive results. MDV3100 is a novel triple-acting oral androgen receptor antagonist, the common antagonist most of us are familiar with today is Casodex. These results were published in the online April 15 version of The Lancet. […]

A Phase I Clinical Trial of DPX-0907 for Advanced Prostate Cancer

As you already know, I am very interested and a strong believer in the future of immunologic therapy. I have written extensively about Provenge and last week I told you about a phase I clinical trial of a Vaccine Therapy for men with progressive stage D0 (non-metastatic) prostate cancer. (http://advancedprostatecancer.net/?p=1419). I want to now let [...]

Salvage Therapy with High Dose Bicalutamide (Casodex) In Non-metastatic Castration-Resistant Prostate Cancer – It Controls PSA and Disease Progression

Researchers at the Department of Urology, Centre Hospitalier Universitaire du Québec (CHUQ), Quebec, Canada evaluated the rate and duration of prostate-specific antigen (PSA) response to high-dose bicalutamide (150 mg) in men with non-metastatic castration-resistant prostate cancer (nmHRPC) as well as its impact on the duration of metastasis-free survival. They concluded that high dose bicalutamide is [...]

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