Cougar Biotech and the FDA Agree on new Abiraterone Trial

An announcement from Market Watch claims that Cougar Biotechnology has come to an agreement with the US Food & Drug Administration (FDA) to conduct an additional Phase III trial of abiraterone acetate in prostate cancer. The currently ongoing and much in demand Phase III trial of abiraterone acetate was designed for prostate cancer survivors who [...]

Lycopene – Just Another Bust!

A group of investigators, interested in the influence of lycopene on both the clinical and laboratory progression of advanced prostate cancer in men with hormone refractory prostate cancer, ran a small prospective Phase II pilot study. The researchers gave lycopene supplementation (15 mg) daily for 6 months to their trial subjects. They performed follow up [...]

Additional Information On Yesterday’s Post About Alpharadin

Charles (Chuck) Maack, Prostate Cancer Advocate/Mentor from the Wichita Kansas Chapter of Us TOO sent me this follow-up to yesterday's post on Alpharadin. Interesting is this drug completed Phase II trials in Norway back in October 2007 involving 64 HRPC patients with more than twice as many patients receiving Alpharadin alive (10 of 33) two [...]

Algeta, Completing A Successful Phase II Trial For Men With Bone Metastases Will Begin Enrolling US Survivors Into A Phase III Trial

Algeta ASA (OSE: ALGETA), has announced that it will begin to enroll US survivors into its Alsympca phase III trial evaluating Alpharadin (radium-223). Alpharadin is designed to be used as a treatment for bone metastases in prostate cancer survivors with hormone-refractory prostate cancer (HRPC). The announcement of the trial follows a successful end-of-phase II meeting [...]

The Role of BRCA1 and BRCA2 Gene Mutations in Advanced Prostate Cancer

Sure, we need more research about prostate cancer, but fortunately we also gain from research into other cancers. The commonly referred to breast cancer genes, BRCA1 and BRCA2 might also increase a man’s risk for developing an aggressive strain of prostate cancer. According to a report in Reuters, men with prostate cancer who also carry [...]

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