Joel Nowak

Denosumab Demonstrates An Increased Time to First Skeletal Event in Men with Metastatic Prostate Cancer vs Zometa

In men with bone metastasis from castration-resistant prostate cancer (CRPC), a monthly subcutaneous injection with denosumab, 120 mg, is superior to Zometa, a multinational group of researchers reported at the American Society of Clinical Oncology annual meeting. The current standard of care is for men with bone metastasis from castration-resistant prostate cancer (CRPC) is to [...]

By Malecare|2017-10-19T10:53:43-04:00August 11th, 2010|Advanced Prostate Cancer, bisphosphonates, Drugs & Treatments, Metastases, Uncategorized, Understanding APC|0 Comments

Carboplatin plus Paclitaxel Therapy after Docetaxel in Men with Metastatic Castrate Resistant Prostate Cancer

UroToday.com published a dual-center study today that confirms that carboplatin and paclitaxel (a taxane product) has an active effect on PSA when used in the treatment of men with castrate resistant prostate cancer (CRPC) after docetaxel (chemotherapy for prostate cancer). […]

By Malecare|2017-10-19T10:53:44-04:00August 5th, 2010|Advanced Prostate Cancer, Cabazitaxel, Chemo Therapy, Chemo Therapy Failure, Drugs & Treatments, Uncategorized, Understanding APC|2 Comments

Should I go on to Hormone Therapy – What about the Risk of Thromboembolic Diseases

(Results from the population-based PCBaSe Sweden) Hormone therapy (ADT) is designed to prevent the manufacturing of testosterone however, testosterone is a very important preventive hormone, especially in the area of heart health. ADT also causes a number of metabolic side-effects including increased body weight, insulin resistance, dyslipidemia, and hyperglycemia. So, how is the risk of [...]

By Malecare|2017-10-19T10:53:45-04:00August 1st, 2010|Advanced Prostate Cancer, Drugs & Treatments, Hormone Therapy, Research, Uncategorized, Understanding APC|0 Comments

Malecare Advanced Prostate Cancer Teleconference

Join us for a conversation about treating advanced stage prostate cancer, with James M. McKiernan, M.D. and Joel Nowak, M.A., M.S.W. […]

By Malecare|2020-02-04T11:31:51-05:00July 30th, 2010|Advanced Prostate Cancer, Drugs & Treatments, General Information, How We Live, On The Horizon, Prostate Ponderings, Research, Uncategorized, Understanding APC|0 Comments

Phase II Study of Nitric Oxide for Men with Increasing PSAs After Primary Treatment for Prostate Cancer

Biochemical recurrence of prostate cancer after primary therapy (PSA only) remains a significant problem. Deciding on the best treatment options for men who have failed primary therapy without documented evidence of metastatic disease remains limited and controversial. Androgen deprivation therapy (ADT), the usual next step for biochemical recurrence does prolong the time to further disease [...]

By Malecare|2017-10-19T10:53:45-04:00July 26th, 2010|Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, Research, Technology, Uncategorized, Understanding APC|7 Comments

Can B7-H3 Expression Serve as a Biomarker of Biochemical Recurrence after Salvage Radiation Therapy for Recurrent Prostate Cancer?

Current knowledge makes it very difficult to predict which men will experience biochemical recurrence (BCR) after salvage radiation therapy (SRT) for recurrent prostate cancer (PCa). We are also lacking in novel targets for adjuvant therapies. At the College of Medicine, Mayo Clinic Florida, Jacksonville, FL., researchers evaluated the association of B7-H3 expression in primary PCa [...]

By Malecare|2010-07-25T10:13:12-04:00July 25th, 2010|Advanced Prostate Cancer, Research, Uncategorized, Understanding APC|0 Comments

Can Our Society Find Its Way To An Honest Dialogue About The Price Of A Human Life?

What is the real cost of approved treatments for advanced prostate cancer and how much we should spend? These questions are rippling through the prostate cancer community and the general population. […]

By Malecare|2017-10-19T10:53:46-04:00July 23rd, 2010|Advanced Prostate Cancer, Advocacy, Cabazitaxel, Chemo Therapy, Drugs & Treatments, General Information, How We Live, Politics of Cancer, Uncategorized, Understanding APC|1 Comment

Possible Role of a BRCA1 Gene Loss in Metastatic Prostate Cancer Progression

Genetic counseling is common place in the world of breast cancer including the evaluation of the BRCA genes. Prostate and breast cancer increasingly been shown to have a relationship, perhaps all the down to the genetic level. Researchers are now understanding, that like in breast cancer, BRCA1 loss preexisting in small sub-populations of prostate cancer [...]

By Malecare|2017-10-19T10:53:46-04:00July 22nd, 2010|Advanced Prostate Cancer, General Information, genetics, Metastases, Uncategorized, Understanding APC|0 Comments

Prostate Cancer- The Good Cancer for Men Over 75 Years!

I know, we all have our prostate cancer story where we are told how lucky we are that we have prostate cancer. The conversation goes on something like, “Oh you are so lucky, you have the GOOD cancer, you should be so thankful.” Then it is often followed up by something like, “My (father) (brother) [...]

By Malecare|2017-10-19T10:53:46-04:00July 19th, 2010|Advanced Prostate Cancer, General Information, How We Live, Personal Experiences, Politics of Cancer, Uncategorized, Understanding APC|5 Comments

An Important Fact from the 2010 AUA Meeting

Findings from the Prostate, Lung, Colorectal and Ovarian (PLCO) screening trial indicate that the strongest predictors of prostate cancer-specific mortality include Gleason 7, body mass index >30, African-American race, PSA level, stage, and high co-morbidity score. Understanding how non-tumor factors affect prostate cancer-specific mortality will help identify those men who may benefit from screening and [...]

By Malecare|2010-07-14T14:41:43-04:00July 14th, 2010|Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, General Information, Uncategorized, Understanding APC|0 Comments