The Clinical Trial for Abiraterone Acetate Has Been Unblinded Yielding Great News For Us All

Ortho Biotech & Development, a unit of Cougar Biotechnology, Inc. has unblinded their Phase 3 study of abiraterone acetate plus prednisone. In the trial the abiraterone was used for the treatment of men with metastatic advanced prostate cancer has progressed following treatment with one or two chemotherapy regimens at least one of which contained docetaxel. [...]

:( Taxotere Burn :(

The taxotere burn is not the hottest, latest dance sweeping the country, it is a little discussed complication that can strike a man while having chemotherapy for the treatment of prostate cancer. If the infusion equipment is not secured tightly or the vein not properly accessed and any of the taxotere is allowed to leak [...]

BRCA2 Mutation Indicates Shorter Survival in Men with Prostate Cancer

A study performed in the UK, reported in the British Journal Cancer (2010), showed that men who have a deleterious germ-line mutation in the breast cancer 2 (BRCA2) gene and who have prostate cancer do not survive as long as men with prostate cancer who are non-carriers. There have been earlier studies that have shown [...]

Finally, CMS Announces A Meeting to Discuss Medicare Coverage for Provenge

The Center for Medicare and Medicaid Services (CMS), the U.S. agency in charge of Medicare, announced yesterday that it has scheduled a meeting to discuss the coverage of Dendreon’s prostate cancer vaccine Provenge. The meeting has been scheduled for this November 17. […]

Pamidronate or Zoledronic Acid – Is There A Difference In the End Results?

Pamidronate and zoledronic acid (bisphosphonates) are a mainstay in the treatment of men with advanced prostate cancer as well as for breast cancer survivors for the prevention of skeletal-related events (SREs). There have been many clinical trials comparing the efficacy and side effect profiles between pamidronate and zoledronic acid among men with advanced prostate cancer. [...]

Part I of III – Managing Taxotere Side Effects – Blood Problems

One of the major problems faced by men on taxotere (chemotherapy) is anemia. Anemia is characterized as a low red blood cell count. It is often the cause of significant fatigue, another major complaint from men on chemotherapy. Aranesp® and Procrit® are both synthetic versions of the naturally occurring hormone, erythropoietin, that stimulates red blood [...]

Does Androgen Deprivation Treatment (ADT) in Men with Castration-Resistant Prostate Cancer Receiving Chemotherapy have a Clinical Benefit?

Is there any reason to continue hormone therapy (ADT) while I have become castrate resistant and I’m starting chemotherapy? This is a common question that is asked by many of us. The real underlying question we are asking is: I feel so terrible now and I am getting ready to add chemotherapy with all of [...]

Caution, Common Medications Impact PSA Measurments

There have been a number of studies that have suggested that some common medications will alter prostate-specific antigen (PSA) levels. Researchers from Stanford University School of Medicine, Stanford, CA., investigated the impact of individual and combinations of common medications thought to impact PSA in a large cross-sectional study of the United States population. […]

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