Three Types of Aggressive Prostate Cancer Have Their Genomes Mapped

Finally, advanced prostate cancer makes it into the genomeic world of cancer. Researchers at the Fred Hutchinson Cancer Research Center and the University of Washington in Seattle published in this week's online edition of the Proceedings of the National Academy of Sciences an announcement that they have mapped the genomes of three different types of [...]

Genome-wide Association Study Identifies a Genetic Variant Associated with Risk for More Aggressive Prostate Cancer

It is estimated that in the United States 200,000 men will be diagnosed with prostate cancer each year with approximately 20% to 30% having clinically aggressive prostate cancer. When diagnosed the standard is to consider factors such as Gleason score and tumor stage to assess a man’s prognosis, however there are no biomarkers to identify [...]

Decreased Prostate Cancer-Specific Survival of Men with BRCA2 Mutations and for Men from Breast Cancer Families

It is fairly common practice for those diagnosed with breast cancer to have genetic testing. Genetic testing is almost unheard of when men are diagnosed with prostate cancer. Current research shows that genetic testing for men with prostate cancer could provide important information about both potential treatment efficacy and prognosis. A recent look at the [...]

Towards An Understanding of the Role of Genetics in Determining Future Treatment Options in Advanced Prostate Cancer – SLCO2B1 and SLCO1B3

We have heard for a period of time that the future of cancer treatment is in genetics. Despite the hubbub, we see very little hard evidence of this in today’s current treatment decisions. Treatment still remains tied into protocols with a strong bias to following a common map. Each map does have little variances, but [...]

One Large Step for Prostate Cancer and One Very Small Step for Men – Whole Genome Sequencing for Prostate Cancer

Yesterday the Prostate Cancer Foundation (PCRF) made a major announcement, it has sequenced the of whole cancer genomes of seven different men with aggressive prostate cancer. This is a historic development in the fight against prostate cancer, however, it is a small step for those of us on the ground. The eventual goal of projects [...]

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