A Brief Update of the Current Landscape of Bone Targeted Therapies for Prostate Cancer

Prostate cancer tends to metastasize to bones as opposed to soft tissue and other organs.   We have no idea why it does have a preference for bone, but it does. Developing bone metastases in prostrate cancer is a very strong negative prognostic indicator. Prostate cancer’s tendency to favor bone over soft tissue causes significant morbidity [...]

Bone Complications Among Prostate Cancer Survivors Having Prolonged Hormone Therapy (ADT)

Androgen deprivation therapy (ADT) and bone complications are the two near universals for men with advanced prostate cancer. A long-term follow up of fifteen (15) years after diagnosis of a population-based cohort of prostate cancer survivors proved to be very informative. The Prostate Cancer Outcomes Study, which enrolled 3533 men diagnosed with prostate cancer between [...]

Now Available: Teleconference about Bone Health and Advanced Prostate Cancer

Today, Malecare posted our latest teleconference with Dr. Neal Shore, M.D.   The conference, which was recorded last week, is about Bone Health and Prostate Cancer.  It discusses the importance of maintaining healthy bones and methods to accomplish this task when facing advanced prostate cancer.  This teleconference was made possible by the generous support of Bayer. [...]

A Common Advanced Prostate Cancer Emergency – Spinal Cord Compression

Spinal cord compression is not an uncommon occurrence in men with advanced prostate cancer. Bones are the most common target of advanced prostate cancer, including the spine. Sadly, there is often a delay in diagnosing spinal cord compression resulting from prostate cancer. These delays in diagnosis can influence the eventual functional outcome. Oncologists, primary care [...]

Request for the Approval of Denosumab to Protect Bones in Men with Advanced Prostate Cancer

Amgen has submitted a supplemental Biologics License Application (sBLA) to the FDA to expand the indication for denosumab (XGEVA) its RANK ligand inhibitor to treat men with castrate-resistant prostate cancer to reduce the risk of developing bone metastases. Although some doctors have already begun to use Xgeva in men with advanced prostate cancer, it is [...]

Watch This Informative Video About Advanced Prostate Cancer & Bone Health

Thanks to Kathy Meade, I just viewed an exceptional video about advanced prostate cancer. It also includes information on bone health, screening, research, the need for funding and the history of prostate cancer treatment. All advocates and men with prostate cancer should learn something by watching the video. The following is the link: http://www.itvisus.com/programs/hbhm/index.asp#ooid=Iza2VhMTqn-tHgaxfstDRMBJ 1b12EW7i [...]