An informative and comprehensive analysis of existing research studies evaluating the merits of early vs. deferred commencement of hormone therapy in men with advanced prostate cancer was recently published. The analysis (Wilt T, Nair B, MacDonald R, Rutks I. Early versus deferred androgen suppression in the treatment of advanced prostatic cancer. Cochrane Database of Systematic [...]
Today, Cougar Biotechnology, Inc. (NASDAQ:CGRB) unveiled the results from its ongoing Phase II clinical trial drug CB7630 (abiraterone acetate). The data was presented at the Prostate Cancer Foundation Scientific Retreat in Lake Tahoe, Nevada. The clinical trial, which is centered at the M.D. Anderson Cancer Center in Texas and was designed to look at the [...]
As advanced prostate cancer progresses it becomes inevitable that we will develop bone metastases. The treatments available are designed to slow disease progression, to relieve pain and to avoid the complications that result from bones being weakened by the cancer. Weakened bones become very susceptible to fractures, with prostate cancer the most likely sight for [...]
The number of men with Hormone Refractory Prostate Cancer (HRCP) is ever increasing; some statisticians feel that it could eventually become the most common cancer in the male population. The clinical variability, the lack of consensus on patients' eligibility for starting a different treatment, and the response criteria seen in literature have made it difficult [...]
In today’s New York Times Gina Kolata wrote a very interesting article about the unreliability of MRIs for diagnostic purposes. She wrote from the perspective of orthopedic injuries, but since MRIs are main stays for us suffering with prostate cancer, there is an important message for us. Her story revolves around a running injury that [...]
Did you have androgen deprivation therapy (ADT)? If you have you probably experienced hot flashes. Up to 80% of men treated with ADT for prostate cancer will experience hot flashes, ranging from very mild to very severe. Along with hot flashes many of us will also have insomnia, fatigue, irritability and a host of other [...]
A study which was funded by Cell Pathways Inc., developer of the drug Exisulind, suggest that Exisulind may delay disease progression in men with recurrent prostate cancer according to Dr. Erik Goluboff, Assistant Professor of Urology at Columbia University College of Physicians & Surgeons, Director of Urology at The Allen Pavilion of New York-Presbyterian Hospital, [...]
Remember when we were younger, I mean 5, 6 and 7 years old. Life was full of hope and dreams. We wanted to be firemen, policemen and astronauts. The future glowed full of our visions of greatness and desires. Nothing could possibly hold us back. Our imaginations ran free, we had no barriers. Now is [...]
When we are diagnosed with prostate cancer, especially with recurrent prostate cancer, we shoulder the emotional burden of telling our loved ones. This burden comes at the very same moment that we too are managing our own emotional response to the news. When diagnosed, we face an uphill emotional battle. At the exact time we [...]
Hair on a man's head offers clues about versatility of a molecule central to Advanced Prostate Cancer. Once again, those of us fighting advanced and recurrent prostate cancer are confronted with contradictory and confusing information. The usual first line treatment for advanced prostate cancer is hormone therapy (ADT). We all know that ADT is short [...]
