Advanced prostate cancer will progress and most of us will face a time when Androgen Deprivation Therapy (ADT) stops working. Most men on ADT take a LHRH agonist, which turns off the production of testosterone (i.e. Lupron) along with a non-steroidal anti-androgen (i.e. Casodex) that prevents the small amount of testosterone that continues to be [...]
The absence of a stromal protein called caveolin-1 appears to be a marker for advanced prostate cancer and for metastasis, researchers from the Kimmel Cancer Center at Jefferson and Harvard Medical School reported in "Cell Cycle." Caveolin-1 has already been shown to be a good biomarker serving as a prognostic factor for breast cancer. The [...]
A new study links hormone therapy for prostate cancer with a higher risk of death in older men who've had serious heart problems. The side effects of hormone therapy can be significant. They include impotence, bone loss, hot flashes, memory problems, fatigue and an increased risk for diabetes and heart disease. In a study appearing [...]
Combined androgen blockade with bicalutamide for advanced prostate cancer: Long-term follow-up of a phase 3, double-blind, randomized study for survival Department of Urology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan has released some very significant survival data about a previously reported, double-blind, randomized, multicenter phase 3 trial. This trial compared combined androgen blockade [...]
Scott Goodwin has been a guest writer on this blog. He has been sharing his experiences and feelings as he continues his journey on chemotherapy. Scott is not doing as well as we all had hoped. His final paragraph says "When does the time come when a man will stop all treatments and try to [...]