Advanced prostate cancer will progress and most of us will face a time when Androgen Deprivation Therapy (ADT) stops working. Most men on ADT take a LHRH agonist, which turns off the production of testosterone (i.e. Lupron) along with a non-steroidal anti-androgen (i.e. Casodex) that prevents the small amount of testosterone that continues to be [...]
The absence of a stromal protein called caveolin-1 appears to be a marker for advanced prostate cancer and for metastasis, researchers from the Kimmel Cancer Center at Jefferson and Harvard Medical School reported in "Cell Cycle." Caveolin-1 has already been shown to be a good biomarker serving as a prognostic factor for breast cancer. The [...]
A new study links hormone therapy for prostate cancer with a higher risk of death in older men who've had serious heart problems. The side effects of hormone therapy can be significant. They include impotence, bone loss, hot flashes, memory problems, fatigue and an increased risk for diabetes and heart disease. In a study appearing [...]
Combined androgen blockade with bicalutamide for advanced prostate cancer: Long-term follow-up of a phase 3, double-blind, randomized study for survival Department of Urology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan has released some very significant survival data about a previously reported, double-blind, randomized, multicenter phase 3 trial. This trial compared combined androgen blockade [...]
Scott Goodwin has been a guest writer on this blog. He has been sharing his experiences and feelings as he continues his journey on chemotherapy. Scott is not doing as well as we all had hoped. His final paragraph says "When does the time come when a man will stop all treatments and try to [...]
Selenium is one of those supplements that were are told is good for us and then we are told it is bad for us. Every six months to a year the story and the recommendations seem to change. According to a study by researchers at Dana-Farber Cancer Institute the University of California, San Francisco higher [...]
A paradoxical, but logical finding, indicates that I am more likely to die from prostate cancer than my fellow pc survivors. In the world of prostate cancer I am a young man. I was diagnosed at 50 years and suffered a recurrence at 55 years, in the prostate cancer world this makes me a young [...]
The Department of Urology, University of Tennessee Health Science Center, Memphis, TN, performed a retrospective study designed to evaluate the overall survival (OS) and disease-specific survival (DSS) in men receiving primary androgen-deprivation therapy (PADT) or salvage medical ADT (SADT) for prostate cancer. The study included men who were diagnosed and treated with ADT between July [...]
When your PSA starts to rise after you have received primary treatment you need to be concerned that your prostate cancer has reoccurred. The first indicator of recurrent prostate cancer is a detectable level of prostate-specific antigen (PSA). Research has demonstrated that PSA doubling time is a reliable tool to distinguish which cancers pose a [...]
That is the big question I am dealing with this week. I have been so pleased with my recent success with lowering my PSA, but the last test has reversed the trend. My PSA has shown a drastic rise. It went from just under .60 to almost 2.0 within a two week period! As we [...]
