We all know it, advanced prostate cancer not only affects the survivor, but it also affects his family. When diagnosed with advanced prostate cancer, the most common treatment is androgen deprivation therapy (ADT) which causes many side effects. These side effects include (but are not limited to) fatigue, nausea, hot flashes, pain, constipation and sexual [...]
There is a brief, but great YouTube video that very simply and clearly explains the current thinking about how and why prostate cancer becomes androgen independent (castrate resistant). View the video by clicking here Joel T Nowak, M.A., M.S.W.
Prostate cancer patients who are treated with a combination of hormone therapy and radiation have a substantially improved chance of survival compared to patients who do not receive radiation, according to interim results of the largest randomized study of its kind presented at the plenary session, November 1, 2010, at the 52nd Annual Meeting [...]
Diagnosed with lymph-node positive prostate cancer, what are the best treatment options? Should you add surgery to hormone therapy? These are important questions which have not yet been adequately answered. To help to begin to answer this question, researchers at Department of Urologic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL. and [...]
Written by our own Richard Wassersug appearing in UroToday.com BERKELEY, CA (UroToday.com) – Much has happened with the use of androgen deprivation to treat prostate cancer (PCa) patients since Charles Huggins first castrated a patient in order to alleviate the symptoms of advanced PCa. Back then, patients were generally elderly and symptomatic with either urethral [...]
Somastatin is a naturally occurring hormone that affects the levels of other hormone production in the body. Its most common drug use today is to treat giantism and acromegaley, a disease characterized by an over abundance of growth hormones. There is laboratory evidence that somastatin analogs such as octreotide acetate (Sandostatin/Sandoz) can affect the growth [...]
One of the earliest hormone therapies (ADT) given to men to treat prostate cancer was estrogen. Estrogen, commonly known as the female hormone, was used as an ADT treatment in the early 1950s. […]
At some point in the progression of advanced prostate cancer the usual initial standard of care, hormone therapy (ADT2 or ADT3), will fail to control the progression of the cancer. Commonly, when ADT does fail we will experience an increase in our PSA scores and often see signs of disease progression on imaging tests. For [...]
Is there any reason to continue hormone therapy (ADT) while I have become castrate resistant and I’m starting chemotherapy? This is a common question that is asked by many of us. The real underlying question we are asking is: I feel so terrible now and I am getting ready to add chemotherapy with all of [...]
We all know that hormone therapy (ADT2) stops the production of testosterone and blocks the little testosterone that might still be produced from entering into the prostate cancer cell to “feed” the cancer. There have been a number of studies that have investigated and concluded that ADT not only stops testosterone, but also has anti-vascular [...]
