Understanding APC

Degarelix Monotherapy vs. Luteinizing Hormone-Releasing Hormone Agonists Plus Antiandrogen Flare Protection For Men With Advanced Prostate Cancer *

There are a number of different flavors of hormone therapy (ADT) used to treat advanced prostate cancer. However, they could be summed up and put into two different categories. 1- The use of luteinizing hormone-releasing hormone (LHRH) agonist therapy (drugs like Lupron and Zoladex) along with short term antiandrogen (AA) flare protection 2- Degarelix, a [...]

By Malecare|2020-02-04T11:51:33-05:00December 4th, 2014|ADT, Advanced Prostate Cancer, Androgan Receptor Inhibitor, degarelix, Drugs & Treatments, General Information, Hormone Therapy, Research, Uncategorized, Understanding APC|0 Comments

Using choline-C11 PET/CT Scans To Predict Survival In Men With Recurrent Prostate Cancer

Choline-C11 PET/CT scans can identify the actual sites of recurrence of prostate cancer in men who have a rising PSA after receiving primary therapy. The question worth asking is if this type of scan might be able to be used for prognostic purposes. Knowing this might influence our treatment decisions as well as our basic [...]

By Malecare|2020-02-04T11:36:42-05:00November 28th, 2014|adjuvant therapy, Advanced Prostate Cancer, Choline C11, Scanning Technology, Uncategorized, Understanding APC|0 Comments

Where Have I been the Past Week?

Over this past week I have not been able to make any post to the blog. I apologize to anybody kept coming back to the blog and didn't see anything new. Two Sunday nights ago I was admitted to the hospital and had an emergency appendectomy the following Tuesday night. Due to my age and [...]

By Malecare|2017-10-19T10:47:42-04:00November 24th, 2014|Advanced Prostate Cancer, General Information, Prostate Ponderings, Uncategorized, Understanding APC|0 Comments

Radiotherapy Should Be Added to Hormone Therapy in Node-Positive Prostate Cancer as the New Standard of Care

In the normal course of events node-positive prostate cancer has typically been excluded from clinical trials. This leaves our oncologists with little evidence to guide the management for those of us who have this flavor of prostate cancer. A recent anaylisis presented at the European Society for Medical Oncology (ESMO) 2014 Congress begins to shed [...]

By Malecare|2020-02-04T10:48:26-05:00November 13th, 2014|ADT, Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, ESMO, Uncategorized, Understanding APC|0 Comments

Bone Complications Among Prostate Cancer Survivors Having Prolonged Hormone Therapy (ADT)

Androgen deprivation therapy (ADT) and bone complications are the two near universals for men with advanced prostate cancer. A long-term follow up of fifteen (15) years after diagnosis of a population-based cohort of prostate cancer survivors proved to be very informative. The Prostate Cancer Outcomes Study, which enrolled 3533 men diagnosed with prostate cancer between [...]

By Malecare|2020-02-04T08:42:24-05:00November 12th, 2014|ADT, Advanced Prostate Cancer, Bone Health, Drugs & Treatments, Hormone Therapy, Uncategorized, Understanding APC|0 Comments

Doctoral Student Develops A Device That Provides An Up-Close Look At Cancer’s Movement In The Body

Sometimes scientific research is amazing! We are so lucky to have so many brilliant and gifted young people interested in conquering cancer. One of these brilliant young people is a doctoral student at Johns Hopkins, Andrew Wong. Mr Wong is a Ph.D. student studying materials science and engineering. Along with his facility advisor he has [...]

By Malecare|2017-10-19T10:47:43-04:00November 7th, 2014|Advanced Prostate Cancer, General Information, Metastases, Research, Uncategorized, Understanding APC|0 Comments

Agent Orange Exposure? Your Children & Grandchildren Might Be At Risk!

A large number of the readers of this blog either have had exposure to Agent Orange or have family members who have had the exposure. We know that for those men exposed their risks for developing prostate cancer are greatly increased. Besides an increased risk of developing the cancer there is evidence that Agent Orange [...]

By Malecare|2020-02-04T12:32:19-05:00November 6th, 2014|Advanced Prostate Cancer, advanced prostate cancer support group, Agent Orange, General Information, Uncategorized, Understanding APC|0 Comments

Long-Term Results of COU-AA-302 Show Abiraterone (Zytiga) Has A Survival Benefit

When the FDA approved Abiraterone with prednisone (Zytiga) in the pre-chemotherapy stage they approved it after an interim analysis of data was performed of the phase III clinical trial (COU-AA-302), The analysis was performed by an independent data monitoring committee that found a significant difference in radiographic progression-free survival (scans that showed no tumor progression [...]

By Malecare|2017-10-19T10:47:43-04:00November 5th, 2014|abiraterone acetate, Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, Uncategorized, Understanding APC, Zytiga|2 Comments

Outcomes Analysis of Pooled Individual Data from Randomized Clinical Trials of Degarelix versus Luteinising Hormone-Releasing Hormone Agonists

Degarelex (Firmagon) (approved by the FDA in December of 2008) is a hormonal therapy drug used to treat advanced prostate cancer that has become metastatic and castrate resistant (mCRPC). Degarelix is a GnRH receptor that binds to the pituitary GnRH receptors, reducing the release of gonadotropins leading to a quick and profound onset that blocks [...]

By Malecare|2017-10-19T10:47:44-04:00November 3rd, 2014|ADT, Advanced Prostate Cancer, Clinical Trials, Drugs & Treatments, General Information, Hormone Therapy, Uncategorized, Understanding APC|0 Comments

Lack of PSA Decline as an Independent Predictor of Biochemical Failure Post Salvage Radiation Therapy

It would be of great advantage to us if we were able to improve the early detection of responders to salvage external beam radiotherapy (RT) after failed radical prostatectomy (RP). Early detection would allow us to make earlier treatment decisions which should provide for better results. In an attempt to better improve our understanding of [...]

By Malecare|2014-10-20T16:06:11-04:00October 20th, 2014|Advanced Prostate Cancer, Bio Chemical Recurrence, biomarkers, Drugs & Treatments, prognostic tools, Radiotherapy, salvage therapy, Uncategorized, Understanding APC|0 Comments