An Increase in the Risk of Second Primary Cancers in Men with Prostate Cancer: A Population-Based Cohort Study

The good news for us is that the survival of men diagnosed with prostate cancer has improved over time. The current 10-year relative survival rate is 99.7%! However, the long survival of men who have prostate cancer raises questions about their risk of a second primary cancer and the need for continued surveillance. A very [...]

Multiple vs. One External Beam Radiation Dose for Palliation of Bone Pain in Men with Prostate Cancer

A man in the advanced prostate cancer online support group has asked, “Why the radiation (external beam to relieve bone pain from prostate cancer and to protect the bones from fractures) is given in so many "mini" doses rather than one or two larger doses. The answer is it doesn't necessarily have to be delivered [...]

Randy Sheffield Shares An Important Warning About ONJ

Randy Sheffield, a member of the Malecare Advanced Prostate Cancer Online support group recently has had his fight with advanced prostate cancer made even more complex when he developed Osteonecrosis of the jaw (ONJ). ONJ is an uncommon but terrible side effect of taking bisphosphonates. Randy wrote a warning to all the members of the [...]

The Well Reviewed Guide to Advanced Prostate Cancer (A Survivor Perspective) Has Been Updated and is Now Available for a free Download

Somehow I have been negligent and not let people know that I have written and posted a major update of my “Guide to Advanced Prostate Cancer.” As in the past, it is available as a free download from the Malecare web site. Helping me to update the book was prostate cancer survivor Craig Pynn and [...]

New ASCO/CCO Prostate Cancer Guidelines Emphasize Quality of Life

It is important that survivors keep up on the professional standards of our doctors to make sure that we receive the best care and the most current care. It is easy for doctors to just do it the way they were first trained, even if their training was twentyor thirty years ago. Recent news includes [...]

FDA Approves Movanik for Opioid Induced Constipation in Non-Cancerous Patients – Does It Also Have A Role in Cancer Survivors?

As prostate cancer progresses so does the pain we will suffer. In the normal course we will also progress on to different drugs to help control the pain. Opioids are one of the most common of these drugs prescribed to help control pain. As with all drugs opioids have many side effects. One of the [...]

Phase 4 PROCEED Trial Shows Earlier Provenge Delays First Chemotherapy Exposure

Provenge or Sipuleucel-T (sip-T) remains not well understood by many prostate cancer survivors as well as some treating physicians. Because Provenge does not immediately control PSA or disease progression it creates a situation where some individuals are skeptical as to its efficacy. This is true despite the clear survival advantage demonstrated in clinical trials. This [...]

Long-term Survival of Extremely Advanced Prostate Cancer Patients Diagnosed with PSA over 500 ng/ml

It is generally believed that combination hormone therapy (ADT 2, 3 or 4) is superior to mono-therapy (with just one drug). With this in mind researchers investigated the survival of hormone-naïve prostate cancer survivors diagnosed with prostate-specific antigen (PSA) over 500 ng/ml. They extracted data of prostate cancer survivors from the Japan Study Group of [...]

Depression In Men Receiving Androgen Deprivation Therapy (ADT)

Yesterday I wrote about the cognitive effects of hormone therapy (ADT), today’s topic is about depression in men on ADT. It is commonly known that men on ADT often experience many physical and psychological side effects of the treatment. One of these side effects to ADT may be associated with increased risk for depression, but [...]

Chemo-Brain and ADT for Advanced Prostate Cancer – Does It Exist?

When I went on my first round of hormone therapy (ADT) I experienced severe cognitive side effects. I found it impossible to concentrate, read and remember anything. I lost the ability to navigate the New York City subways no less drive my car to a destination. Occasionally, when I was attempting to navigate the subway [...]

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