Alpha Blockers Linked to Prostate Cancer Relapse

A retrospective study has just been published that shows that the risk of experiencing a biochemical recurrence (PSA recurrence) after radical prostatectomy to treat prostate cancer increased significantly in men who received alpha blockers for lower urinary tract symptoms (LUTS) after surgery. When compared to men who did not receive alpha blockers, those who did [...]

The Really Big Factor in Prostate Cancer Deaths Is Age – Can Rationing Save Money?

Is it a subtle form of healthcare rationing with the goal of saving money at the expense of lives? Maybe that is what is going on. Older men are not economically as valuable to society as other individuals, in many people’s eyes they are actually a burden. Can a solution to the problem be to [...]

Attacking Androgen Receptor Signaling In Castrate Resistant Prostate Cancer

Advanced prostate cancer eventually progresses and becomes castration resistant (CRPC) despite the fact that it is exquisitely sensitivity to androgen deprivation therapy. There has been recent evidence that prostate cancer progression at the CRPC stage is still mediated by androgen receptor signaling, so it seems that subsequent androgen receptor targeting may further contribute to disease [...]

On The Horizon – Some More Information & An Update On MDV3100

Many of us are aware of the newly approved drug Zytiga (abiraterone). It had demonstrated a survival advantage for men who are castrate resistant and failed chemotherapy. Zytiga was approved by the FDA in April and many of us with advanced prostate cancer have been taking advantage of the drug. You can learn more about [...]

Eating Eggs Increases the Chance of Developing Lethal Prostate Cancer

We all know that diet does effect the development of more lethal forms of prostate cancer. Red meat and dairy products are on the “NO” list while fish oil is a “YES”. Now, it looks as if the “NO” list has just been expanded! A large study has found that eating eggs may increase men's [...]

Three Types of Aggressive Prostate Cancer Have Their Genomes Mapped

Finally, advanced prostate cancer makes it into the genomeic world of cancer. Researchers at the Fred Hutchinson Cancer Research Center and the University of Washington in Seattle published in this week's online edition of the Proceedings of the National Academy of Sciences an announcement that they have mapped the genomes of three different types of [...]

FDA Approves New Indications for Prolia® (Denosumab) for the Treatment of Bone Loss in Men with Prostate Cancer Undergoing ADT

Amgen announced that the U.S. Food and Drug Administration (FDA) has approved two new indications for Prolia® (denosumab) as a treatment to increase bone mass in men receiving androgen deprivation therapy (ADT) for non-metastatic prostate cancer. Men receiving ADT are at high risk for developing fractures, including vertebral fractures, which can cause paralysis. "Bone loss [...]

Genetics & Calcium Might Increase Risk for Prostate Cancer In the African-American Men

A study by at Wake Forest Baptist Medical Center in Winston-Salem N.C., Keck School of Medicine at the University of Southern California (USC) and the Cancer Prevention Institute of California suggests that a high intake of calcium causes prostate cancer among African-American men who are genetically good absorbers of the mineral. According to Gary G. [...]

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