The state of cancer care is in crisis and getting worse. There is an ever growing demand for cancer care, a shrinking workforce, rising healthcare costs and an increasing complexity of treatment of cancer. According to the Institute of Medicine (IMO) cancer care in America is in a deep crisis! In analysing the current state [...]
On the advanced prostate cancer online support group there have been some questions raised about how we know when drugs like Zytiga and Xtandi have stopped working. Knowing this as soon as possible is important so that you can quickly move on to the next treatment without giving the prostate cancer time to progress and [...]
Someone on the advanced prostate cancer online support group ask about what are the criteria to go into hospice care. One individual replied that you would need to be within 6 months of your potential death. Another person replied from their individual experience. They said, “Hospice in CT doesn’t have a life expectancy strictly attached [...]
A post from Alan on the Advanced Prostate Cancer On-Line Support Group shared a link, which should interest all of us. It should interest us all because it will have an effect on each and every one of us, whether we are a prostate cancer survivor, if we become one in the future. Actually the [...]
Some bad news was reported today. Results from the Phase 3 randomized, double-blind clinical trial (Study 043) comparing Yervoy 10 mg/kg (ipilimumab) (n=399) to placebo (n=400) following radiation in men with advanced metastatic castration-resistant prostate cancer (mCRPC) who have received prior treatment with docetaxel showed no increase in overall survival. Yervoy is an immunotherapy which [...]
Mama might have been correct, eat your yogurt. Many of us already know that a healthy gut with plenty of probiotics to support your gastrointestinal health is absolutely critical to boosting your immune system. Experts say that gut flora could account for as much as 80% of our immune system! A study from the University [...]
Many clinicians are concerned when a patient comes to them with prostate cancer that has been shown to have perineural invasion (PNI). PNI is defined as the presence of prostate cancer found by biopsy that tracks along or around a nerve within the perineural space. The presence of PNI has been a concern because of [...]
We have many new drugs that have been recently approved to treat advanced prostate cancer. Two of these drugs are abiraterone (Zytiga) and enzalutamide (Xtandi). These drugs offer new hope to men with advanced prostate cancer after the cancer has become resistant to hormone therapies (called "castration-resistant prostate cancer"). These drugs are a real breakthrough, [...]
Researchers at Johns Hopkins has concluded that metastasis-free survival appeared to independently predictor of overall survival (OS) in men with recurrent prostate cancer who underwent androgen deprivation therapy (ADT) after developing metastases. Men with biochemically recurrent prostate cancer (PSA only) tend to survive for long periods so the FDA gold standard for clinical trial endpoint [...]
The first line of treatment for advanced prostate cancer is Androgen (male hormone) Deprivation Therapy or ADT. Once the PSA progresses (climbs) while still on ADT and with testosterone levels
