Today most doctors rely on their personal evaluation or objective response criteria (OR) of a man to know when docetaxel chemotherapy has stopped working. The earlier this determination can be accurately made the quicker an alternative treatment can e put into place. Personal evaluations without any validated tools are unreliable and never consistent among doctors. [...]
African American men suffer from Prostate Cancer more than anyone, anywhere. If we want better treatments, then we've got to tell folks what it means to be a African American man diagnosed with Prostate Cancer. Please go to http://twiceasmany.org/prostate_cancer_story/ and write a few paragraphs about your experience with prostate cancer OR email twiceasmany@malecare.org and we'll [...]
There have been prior studies that have shown that the generic and inexpensive drug Metformin (used to treat diabetes) could be repurposed and used to decrease the risk of developing prostate cancer as well as to treat prostate cancer. Previous studies suggested that metformin is associated with decreased risk of cancer; however, results specifically addressing [...]
Radium-223 dichloride (Xofigo) has been approved as an intravenous radiotherapy for men with castration-resistant prostate cancer (CRPC) who have multiple osseous (bone) metastases. Most often, it is used in men who have too many metastases to treat with spot radiation. Xofigo works by mimicking calcium that is attracted to bones. To be successful the drug [...]
Malecare has been an active and early member of the Defense Health Research Consortium. The consortium currently consists of 47 different organizations, which educate and advocate for research Department of Defense funding for multiple different diseases and syndromes. The consortium’s goal is to lobby Congress to continue to and to expand support for the Department [...]
Presented in a poster at the recent European Society of Medical Oncologist (ESMO) there was a data update of the phase 3 clinical trial (CA184-043) which evaluated overall survival (OS) in men having radiotherapy (RT) followed by either the immunologic drug Ipilimumab (Ipi) or with a placebo. Initially, this trial did not meet its endpoint [...]
On April 8th I post on this blog an article called The Cholesterol In Your Diet Might Be Causing Your Prostate Cancer To Spread (http://advancedprostatecancer.net/?p=5156). Since I published this I have received some feedback, which has included people asking if they should take statins to control their cholesterol levels. Statin drugs do help control cholesterol [...]
In my commitment to report “On the Horizon” treatments for advanced prostate cancer today I will discuss an investigational treatment known as Tasquinimod. It is an experimental treatment that is both an immunotherapy and anti-angiogenic agent (designed to prevent the development of blood vesicles which would feed a tumor allowing its growth). In phase 2 [...]
Research performed at the University of Queensland has shown that a diet, which is high in cholesterol, might increase the spread of prostate cancer tumors to lymph nodes, lungs and bones. According to the UQ Diamantina Institute study leader Dr Michelle Hill this research highlighted why it is important for men with prostate cancer to [...]
Despite its approval five years ago sipuleucel-T (Provenge) remains one of the most controversial treatments available for men with castrate resistant metastatic prostate cancer (mCRPC). Provenge has its advocates (Full Disclosure- I am) and it has many detractors. The detractors argue that it doesn’t work and they hang their hat on the argument that it [...]
