We know that Abiraterone (Zytiga) extends life, but we also know that its side effects can be harsh, especially in elderly men (men over 75 years). We also know that men with metastatic, castrate resistant prostate cancer (mCRPC) have a limited potential life expectancy. Given these facts, it is important to know if, despite being [...]
Because of the large amount of prostate cancer screening there has been a major shift in initial staging in prostate cancer in western countries, with the incidence of metastases at diagnosis decreasing from over 50% in the 1970s to currently less than 10%. Despite this very significant drop in late stage diagnoses prostate cancer is [...]
There have been some randomized studies that have shown that when prednisone is used in combination with docetaxel (chemotherapy) there is an improved survival in men who have metastatic castration-resistant prostate cancer (mCRPC). To add to our understanding of the possible clinical value of this combination of drugs some researchers have retrospectively evaluated whether the [...]
In an analysis of outcomes reported in the Journal of Clinical Oncology, men who were diagnosed with lymph node-positive prostate cancer (no bone involvement) who went on to receive targeted radiation (adjuvant radiotherapy) enjoyed a survival benefit over those individuals who did not have this therapy. This finding was specifically for men with both low-volume [...]
Are you stressed? If you are and you have been treated for clinically localized prostate cancer you are at a 66% increased risk of dying from your prostate cancer! Research has shown that high stress levels are associated with an increased rate of prostate cancer (PCa) specific mortality among men treated for clinically localized prostate [...]
Clinical trials for treatment of men with advanced prostate cancer often don’t include men who are considered very elderly (aged over 80 years). So, even if we know that a treatment is tolerable and effective in the average man, we can not assume that it would also be in the very elderly, especially in reference [...]
Urinary incontinence post-prostatectomy is a too common complaint from men. Although the actual degree of incontinence suffered ranges from being minor, or a simple and small amount of post urination dribble, to a complete and total inability to control any urine flow, the most bothersome issues that significantly affects a man’s quality of life (QoL) [...]
Traditional hormone therapy usually consists of two types of drugs; GnRH agonists (like Lupron and Zoladex) and antiandrogens (Casodex). Although they both are drugs that manipulate the hormone system their modes of action are different. GnRH agonists block the production of the male hormone testosterone while the antiandrogen drug blocks the ability of the prostate [...]
There is a lot of evidence that pre-treatment rehabilitation (prehabilitation or pre-hab) both speeds up and benefits a patient’s recovery after surgical orthopedic treatment for knee and hip replacement as well as cardiac conditions. Having pre-hab, which is often covered by insurance after orthopedic surgery, is pretty standard. Now, based on an article published in [...]
The problems created by Senator McCain continue to be ever present. Our friend, Senator Durbin has asked that we provide his office with additional background about the military nature of the research performed by the Congressionally Directed Medical Research Programs (CDMRP), including the Prostate Cancer Research Program (PCRP). In addition there is a very misguided [...]
